Results 111 to 120 of about 8,950,425 (295)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The regulation of alginate biosynthesis via cyclic di-GMP signaling

, 2020
Bacterial alginates are anionic exopolysaccharides, which are produced by Pseudomonas and Azotobacter species. Bacterial cells embedded in extracellular polymeric substances such as alginates have a survival advantage as they are protected against ...
Rehm, BHA, Moradali, MF
core   +1 more source

Carrier frequency offsets estimation for distributed MIMO system based on SOMP method

Tongxin xuebao, 2018
By utilizing the half invariant property of high-order cyclic cumulants,the equation of signals and its high-order cyclic cumulants was rederivated first.Then simultaneous orthogonal matching pursuit (SOMP) method was used to jointly reconstruct multiple
Yanyan HUANG, Hua PENG
doaj   +2 more sources

A Design of NLOS Communication Scheme Based on SC-FDE with Cyclic Suffix for UAV Payload Communication

Drones
Non-line-of-sight (NLOS) communication with severe loss always leads to performance degradation in unmanned aerial vehicle (UAV) payload communication. In this paper, a UAV NLOS communication scheme based on single-carrier frequency domain equalization ...
Peng Wang, Xin Xiang, Rui Wang, Pengyu Dong, Qiao Li   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Multi-Metals CaMgAl Metal-Organic Framework as CaO-based Sorbent to Achieve Highly CO₂ Capture Capacity and Cyclic Performance. [PDF]

Materials (Basel), 2020
Wu SC, Chang PH, Lin CY, Peng CH.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Bearing Behaviors of Grouted Sleeve Connections After High Temperature Followed by Water Cooling Under Cyclic Loading

Buildings
As a common rebar connector in prefabricated projects, the grouted sleeve connection (GSC) affects structural performance during fire and seismic events.
Wangxi Zhang, Jialu Wang, Yibo Zhou, Jia Wang, Weijian Yi   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

On Improvements of Cyclic MUSIC

EURASIP Journal on Advances in Signal Processing, 2005
Many man-made signals encountered in communications exhibit cyclostationarity. By exploiting cyclostationarity, cyclic MUSIC has been shown to be able to separate signals with different cycle frequencies, thus, to be able to perform signal selective ...
Yan Huiqin, Fan H Howard
doaj   +1 more source