Results 101 to 110 of about 220,758 (314)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Strain Space Multiple Mechanism Model for Clay Under Monotonic and Cyclic Loads [PDF]

, 2015
[The 6th International Conference on Earthquake Geotechnical Engineering (6ICEGE)] 1-4 November 2015; Christchurch, New Zealand.The strain space multiple mechanism model, originally developed for cyclic behavior of granular materials such as sand, is ...
Ozutsumi, O., Iai, S., Ueda, K.
core  

Performance of Pressure Equalized Rainscreen Walls under Cyclic Loading*

Journal of Thermal Insulation and Building Envelopes, 1992
CIB '92: World Building Congress, May 18, 1992, Montreal, Quebec ...
Baskaran, B. A., Brown, W. C.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Behaviour of CFRP strengthened CHS members under monotonic and cyclic loading [PDF]

, 2019
Tubular hollow members, though used in many civil and mechanical applications, are highly vulnerable structural elements when subjected to cyclic loading.
Tafsirojjaman, T., Zhao, Xiao-Ling, Fawzia, Sabrina, Thambiratnam, David   +3 more
core   +1 more source

Carrier frequency estimation method of time-frequency overlapped signals based on cyclic correntropy spectrum

Tongxin xuebao, 2018
According to the performance degradation problem of the carrier frequency estimation method of time-frequency overlapped BPSK signals in Alpha-stable distribution noise,a novel carrier frequency estimation algorithm of the time-frequency overlapped BPSK ...
Tianshuang QIU, Xing CHEN, Jitong MA, Jingchun LI, Rong LI   +4 more
doaj   +2 more sources

Improved Lithium Storage Properties of the Reduced Graphene Oxide/Graphite Composites Based on Functional Groups Control Synthesis

International Journal of Electrochemical Science, 2019
For lithium-ion batteries (LIBs), poor initial coulombic efficiency and poor cyclic performance of graphene oxide (GO) are facing great challenge in commercial application.
Danhua Jiao, Zhengwei Xie, Qi Wan, Zhikai Wei, Xinxiu Yan, Faheem K. Butt, Meizhen Qu   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Electrochemical Properties of Graphene-based All-solid-state Planar Supercapacitors

Journal of Harbin University of Science and Technology, 2018
For a problem of low performance of planar supercapacitors, graphene films were prepared by a method of direct growth on silicon wafers as electrodes, and PVA/H2SO4 is used as gel electrolyte.
ZHANG Guang-yu, LIU Lin-jing, XU Rui, WANG Xin, LI Chuang, Lv Yin-lin, CHEN Yu-juan, ZHU Da-fu, YANG Xin-rui   +8 more
doaj   +1 more source