Results 111 to 120 of about 825,768 (324)

An Upper Bound on the Number of $(132,213)$-Avoiding Cyclic Permutations

open access: yes, 2019
We show a $n^2 \cdot 2^{n/2}$ upper bound on the number of $(132,213)$ avoiding cyclic permutations. This is the first nontrivial upper bound on the number of such permutations.
Huang, Brice
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

On the $\operatorname{rix}$ statistic and valley-hopping [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science
This paper studies the relationship between the modified Foata$\unicode{x2013}$Strehl action (a.k.a. valley-hopping)$\unicode{x2014}$a group action on permutations used to demonstrate the $\gamma$-positivity of the Eulerian polynomials$\unicode{x2014 ...
Nadia Lafrenière, Yan Zhuang
doaj   +1 more source

Random and exhaustive generation of permutations and cycles

open access: yes, 2007
In 1986 S. Sattolo introduced a simple algorithm for uniform random generation of cyclic permutations on a fixed number of symbols. This algorithm is very similar to the standard method for generating a random permutation, but is less well known.
D. Gries   +8 more
core   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Permuting operations on strings: Their permutations and their primes [PDF]

open access: yes, 2009
We study some length-preserving operations on strings that permute the symbol positions in strings. These operations include some well-known examples (reversal, circular or cyclic shift, shuffle, twist, operations induced by the Josephus problem) and ...
Asveld, Peter R.J.
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Permutability graph of cyclic subgroups

open access: yes, 2015
Let $G$ be a group. \textit{The permutability graph of cyclic subgroups of $G$}, denoted by $ _c(G)$, is a graph with all the proper cyclic subgroups of $G$ as its vertices and two distinct vertices in $ _c(G)$ are adjacent if and only if the corresponding subgroups permute in $G$.
Rajkumar, R., Devi, P.
openaire   +2 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy