Results 31 to 40 of about 516,804 (240)

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

Encrypting Multiple Images With an Enhanced Chaotic Map

open access: yesIEEE Access, 2022
A multiple-image encryption scheme based on an enhanced chaotic map is proposed. This scheme combines multiple grayscale images into three planes. An amplified sine map is used to generate a dynamic permutation table and a chaotic sequence.
Dolendro Singh Laiphrakpam   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Dynamic Injection and Permutation Coding for Enhanced Data Transmission

open access: yesEntropy
In this paper, we propose a novel approach to enhance spectral efficiency in communication systems by dynamically adjusting the mapping between cyclic permutation coding (CPC) and its injected form.
Kehinde Ogunyanda   +2 more
doaj   +1 more source

GRUP PERMUTASI SIKLIS DALAM PERMAINAN SUIT

open access: yesInfinity, 2012
Makalah ini merupakan kajian konsep grup permutasi dalam sebuah permainan suit. Grup permuatasi yang terdapat dalam permainan suit adalah grup permutasi yang siklis.
Bagus Ardi Saputro
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On the permutation polytopes of some cyclic groups

open access: yesSpecial Matrices
In this article, we study the combinatorics of permutation polytopes of some cyclic groups, denoted by P⟨g⟩P\langle g\rangle where g∈Sng\in {S}_{n}. We give a formula on the dimension and the number of vertices of the smallest faces containing two given
Chen Zhi, Yang Zhiwen, Zhu Kebin
doaj   +1 more source

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