Results 31 to 40 of about 516,804 (240)
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
Encrypting Multiple Images With an Enhanced Chaotic Map
A multiple-image encryption scheme based on an enhanced chaotic map is proposed. This scheme combines multiple grayscale images into three planes. An amplified sine map is used to generate a dynamic permutation table and a chaotic sequence.
Dolendro Singh Laiphrakpam +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Dynamic Injection and Permutation Coding for Enhanced Data Transmission
In this paper, we propose a novel approach to enhance spectral efficiency in communication systems by dynamically adjusting the mapping between cyclic permutation coding (CPC) and its injected form.
Kehinde Ogunyanda +2 more
doaj +1 more source
GRUP PERMUTASI SIKLIS DALAM PERMAINAN SUIT
Makalah ini merupakan kajian konsep grup permutasi dalam sebuah permainan suit. Grup permuatasi yang terdapat dalam permainan suit adalah grup permutasi yang siklis.
Bagus Ardi Saputro
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On the permutation polytopes of some cyclic groups
In this article, we study the combinatorics of permutation polytopes of some cyclic groups, denoted by P⟨g⟩P\langle g\rangle where g∈Sng\in {S}_{n}. We give a formula on the dimension and the number of vertices of the smallest faces containing two given
Chen Zhi, Yang Zhiwen, Zhu Kebin
doaj +1 more source

