Results 51 to 60 of about 7,570 (298)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Let f:X → X be a continuous map defined from a topological space X into itself. We discuss the problem of analyzing and computing explicitly the set Per(fp) of periods of the p-th iterate ...
Cánovas J.S., Linero Bas A.
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On a problem of cyclic permutations of integers
AbstractWe consider a problem of cyclic permutations of integers arising in the field of memory technologies for computer systems, and we solve it in the more general case of reals.
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
GRUP PERMUTASI SIKLIS DALAM PERMAINAN SUIT
Makalah ini merupakan kajian konsep grup permutasi dalam sebuah permainan suit. Grup permuatasi yang terdapat dalam permainan suit adalah grup permutasi yang siklis.
Bagus Ardi Saputro
doaj +1 more source
Permutations over cyclic groups
Generalizing a result in the theory of finite fields we prove that, apart from a couple of exceptions that can be classified, for any elements $a_1,...,a_m$ of the cyclic group of order $m$, there is a permutation $π$ such that $1a_{π(1)}+...+ma_{π(m)}=0$.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In this paper, we introduce and study a tripled system of three associated fractional differential equations. Prior to proceeding to the main results, the proposed system is converted into an equivalent integral form by the help of fractional calculus ...
Mohammed M. Matar +2 more
doaj +1 more source
Analyzing random permutations for cyclic coordinate descent
We consider coordinate descent methods for minimization of convex quadratic functions, in which exact line searches are performed at each iteration. (This algorithm is identical to Gauss-Seidel on the equivalent symmetric positive definite linear system.) We describe a class of convex quadratic functions for which the random permutations version of ...
Stephen J. Wright 0001, Ching-pei Lee
openaire +2 more sources

