Results 71 to 80 of about 71,552 (319)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Generalized triangulations, pipe dreams, and simplicial spheres [PDF]
Discrete Mathematics & Theoretical Computer Science, 2011 We exhibit a canonical connection between maximal $(0,1)$-fillings of a moon polyomino avoiding north-east chains of a given length and reduced pipe dreams of a certain permutation.
Luis Serrano, Christian Stump
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Permutation Decoding and the Stopping Redundancy Hierarchy of Cyclic and Extended Cyclic Codes
, 2008 We introduce the notion of the stopping redundancy hierarchy of a linear block code as a measure of the trade-off between performance and complexity of iterative decoding for the binary erasure channel.
Hehn, Thorsten +3 more
core +1 more source
Cyclic Permutations of Sequences and Uniform Partitions [PDF]
The Electronic Journal of Combinatorics, 2010 Let $\vec{r}=(r_i)_{i=1}^n$ be a sequence of real numbers of length $n$ with sum $s$. Let $s_0=0$ and $s_i=r_1+\ldots +r_i$ for every $i\in\{1,2,\ldots,n\}$. Fluctuation theory is the name given to that part of probability theory which deals with the fluctuations of the partial sums $s_i$.
Huang, Po-Yi, Ma, Jun, Yeh, Yeong-Nan
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Centralizers of automorphisms permuting free generators
Open Mathematics, 2019 By σ ∈ Skm we denote a permutation of the cycle-type km and also the induced automorphism permuting subscripts of free generators in the free group Fkm.
Macedońska Olga, Tomaszewski Witold
doaj +1 more source
Comparative analysis of methods for identifying recurrent copy number alterations in cancer. [PDF]
PLoS ONE, 2012 Recurrent copy number alterations (CNAs) play an important role in cancer genesis. While a number of computational methods have been proposed for identifying such CNAs, their relative merits remain largely unknown in practice since very few efforts have ...
Xiguo Yuan +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Karpatsʹkì Matematičnì Publìkacìï, 2014 The aim of this article is to describe exponent matrices of Gorenstein tiled orders. The necessary and sufficient condition for possibility such to construct a Gorenstein tiled order which has given orders over some discrete valuation ring (the unique ...
V. Kiricenko +4 more
doaj +1 more source