Results 101 to 110 of about 227,971 (307)

Effect of stress direction on the cyclic resistance of sand

, 2018
In total, 55 undrained cyclic torsional shear tests were conducted at a constant mean confining stress, σ0m, constant intermediate principal stress ratios, b = (σ2 − σ3)/(σ1 − σ3), and principal stress directions, α.
Fardin Jafarzadeh, Mostafa Zamanian
core   +1 more source

Evaluation of Cyclic Fatigue Resistance of Novel Replica-Like Instruments in Static Test Model

Applied Bionics and Biomechanics
Introduction. The aim of our study is to comparatively analyze the canal cyclic fatigue resistance of widely used rotary file systems, including EndoArt Touch Gold (ETG), Perfect MTF Plus Gold (PPG), Fanta V-Taper Gold (FVG), and ProTaper Next (PTN ...
Uğur Aydın, Melih Özdemir, Emre Çulha, Muazzez Naz Baştürk Özer, Bilal Turan   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Evaluation of cyclic fatigue resistance of modern Nickel–Titanium rotary instruments with continuous rotation

Giornale Italiano di Endodonzia, 2017
Aim: The aim of present study was to compare cyclic fatigue resistance of three modern Ni–Ti instruments used with continuous rotation. Materials and methods: For this study 3 groups of rotating instruments with continuous rotation (HyFlex EDM, Twisted ...
Massimo Amato, Giuseppe Pantaleo, Dina Abdellatif, Andrea Blasi, Roberto Lo Giudice, Alfredo Iandolo   +5 more
doaj   +1 more source

The role of cyclic nucleotides in bacterial antimicrobial resistance and tolerance

Trends in Microbiology
Nucleotide signalling molecules - mainly cyclic 3',5'-adenosine phosphate (cAMP), bis-(3',5')-cyclic diguanosine monophosphate (c-di-GMP), and bis-(3',5')-cyclic diadenosine monophosphate (c-di-AMP) - contribute to the regulation of cellular pathways. Numerous recent works have focused on the involvement of these cyclic nucleotide phosphates (cNPs) in ...
Yi Liu, Claudia Blanco-Toral, Gerald Larrouy-Maumus   +2 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Constitutive modelling of the behaviour of clays under cyclic loading

, 1989
Includes bibliography.This research work involved the implementation of a constitutive model based on plasticity theory to model the behaviour of a clay under cyclic loading.
Sellers, E J
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Effect of continuous rotary and reciprocating motions on cyclic fatigue resistance of two different nickel–titanium endodontic files: An in vitro study

Endodontology
Aim: The objectives of this study were to evaluate and compare the cyclic fatigue resistance (CFR) of TruNatomy (TRN) and WaveOne Gold (WOG) nickel–titanium files subjected to continuous rotary and reciprocating motions. Methods: Forty files were divided
Rashmeet Nagpal, Dakshita Joy Sinha, Ruchi Rathi, Aditya Gupta, Nikhil Puri, Rahul Paul   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source