Results 91 to 100 of about 227,971 (307)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Experimental response of RC columns built with plain bars under unidirectional cyclic loading
, 2012 A large number of existing reinforced concrete (RC) buildings structures were designed and built before mid-70’s, when the reinforcing bars had plain surface and prior to the enforcement of the modern seismic-oriented design philosophies.
Costa, A. +3 more
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The resistance ratchet: theoretical implications of cyclic selection pressure [PDF]
, 2020 Objectives: To investigate the effects of cyclic antibiotic selection pressure on resistance in a simple mathematical model. Methods: The model assumed that resistance in microbial ecologies changes slowly with changing selection pressure, at a rate ...
J T Magee
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HEAT RESISTANCE OF GRAPHITIZED STEEL
Nauka ta progres transportu, 2014 Purpose. The investigation of temperature dependences of steels' mechanical properties and heat resistance under conditions of thermal cyclic loads. It's necessary to determine the mechanical properties and heat resistance indices of graphitized steels ...
V. O. Savchenko
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Unidirectional cyclic resistance of Ticino and Toyoura sands from centrifuge cone penetration tests
, 2016 The evaluation of the undrained cyclic resistance of sandy deposits is required to forecast the soil behaviour during an earthquake (liquefaction, cyclic mobility); due to the difficulties in obtaining undisturbed samples of most liquefiable soils, it is
FIORAVANTE, Vincenzo, GIRETTI, Daniela
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
, 2012 The information available in the literature about the cyclic behaviour of reinforced concrete elements with plain reinforcing bars is scarce. As a consequence, the influence of bar slippage in elements with plain bars is not yet comprehensively ...
Costa, A. +3 more
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