Results 71 to 80 of about 227,971 (307)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Applied Ocean ResearchCyclic loads induced by environmental factors such as wind, waves, and currents can lead to degradation in pile performance, affecting settlement accumulation and bearing capacity evolution. This paper presents a comprehensive investigation through model
Pan Zhou +5 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Restorative Dentistry & Endodontics, 2017 Objectives The aim of this study was to evaluate the cyclic fatigue resistance of the ProTaper Universal D1 file (Dentsply Maillefer) under continuous and adaptive motion. Materials and Methods Forty ProTaper Universal D1 files were included in this
Taha Özyürek +2 more
doaj +1 more source
The resistance ratchet: theoretical implications of cyclic selection pressure [PDF]
Journal of Antimicrobial Chemotherapy, 2005 To investigate the effects of cyclic antibiotic selection pressure on resistance in a simple mathematical model.The model assumed that resistance in microbial ecologies changes slowly with changing selection pressure, at a rate proportional to the difference between the current resistance level and the resistance level that would be in equilibrium with
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fracture resistance of additively or subtractively manufactured resin-based definitive crowns: Effect of restorative material, resin cement, and cyclic loading. [PDF]
OBJECTIVE To evaluate how restorative material, resin cement, and cyclic loading affect the fracture resistance of resin-based crowns fabricated by using additive or subtractive manufacturing.
Abou-Ayash, Samir +6 more
core +1 more source
, 2023 The present study provides insight into the cyclic behavior of unreinforced and geogrid-reinforced coral sand. To achieve these goals, stress-controlled undrained cyclic triaxial tests were conducted on medium-dense coral sand with and without geogrid ...
Augustine Korli Lawer +7 more
core +1 more source
A comparison of two reciprocating instruments using bending stress and cyclic fatigue tests
Brazilian Oral Research, 2015 The aim of this study was to comparatively evaluate the bending resistance at 45º, the static and dynamic cyclic fatigue life, and the fracture type of the WaveOne (Dentsply Maillefer, Ballaigues, Switzerland) 25-08 and Reciproc (VDW, Munich, Germany) 25-
Pantaleo SCELZA +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source