Results 81 to 90 of about 332,414 (335)

Assessing Liquefaction Risk at Timika Steam Power Plant through Cyclic Stress Ratio Analysis Using Borehole Data

open access: goldJurnal Teknik Pengairan
Suwanto Marsudi   +5 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Experimental study on mechanical properties of Xiaojihan coal samples under plastic flow

open access: yesMeikuang Anquan, 2021
In order to study the plastic flow properties and hysteresis characteristics of Xiaojihan main water-bearing coal seam under the influence of mining, the axial cyclic loading and unloading tests under different confining pressures were carried out. When
YOU Wenqiang, GUO Jingna, WANG Guanghui
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Experimental study on cumulative deformation characteristics of coral sand under long-term cyclic loading

open access: yesYantu gongcheng xuebao, 2019
The drained triaxial shear tests on isotropic and K0 consolidation of coral sand samples taken from the South China Sea reveal that the consolidation path has a significant effect on the strength characteristics of the coral sand.
HE Shao-heng 1, LIU Zhi-jun 2, XIA Tang-dai 1, ZHOU Hong-xing 2, YU Bing-qi 1
doaj   +1 more source

On damping created by heterogeneous yielding in the numerical analysis of nonlinear reinforced concrete frame elements

open access: yes, 2015
In the dynamic analysis of structural engineering systems, it is common practice to introduce damping models to reproduce experimentally observed features.
Cottereau, Régis, Jehel, Pierre
core   +3 more sources

Fatigue crack growth rates for offshore wind monopile weldments in air and seawater: SLIC inter-laboratory test results [PDF]

open access: yes, 2016
The majority of fatigue crack growth (FCG) data sets available on steels in air and seawater environments are several decades old and may not be appropriate for structural integrity assessment of offshore wind turbine foundations, which are fabricated ...
Brennan, Feargal P.   +2 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Mechanical Behavior Evolution and Damage Characterization of Coal under Different Cyclic Engineering Loading

open access: yesGeofluids, 2020
The cyclic loading causes the strength change of porous rocks, which can be frequently encountered in underground coal mining. In order to quantify the cumulative damage of porous coal, multilevel uniaxial cyclic compressive tests were carried out ...
Huajun Wang, Jian Li
doaj   +1 more source

Deformation characteristics of saturated remolded loess under cyclic traffic loads

open access: yesYantu gongcheng xuebao, 2022
To study the deformation laws of saturated remolded loess under the rotation of principal stress axis, the cyclic triaxial tests and cyclic traffic load tests on the saturated remolded loess under drainage are carried out by using the hollow cylinder ...
WENG Xiao-lin 1, HU Ji-bo 1, JIA Yang 2, ZHOU Shang-qi 1
doaj   +1 more source

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