Results 81 to 90 of about 332,414 (335)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Experimental study on mechanical properties of Xiaojihan coal samples under plastic flow
In order to study the plastic flow properties and hysteresis characteristics of Xiaojihan main water-bearing coal seam under the influence of mining, the axial cyclic loading and unloading tests under different confining pressures were carried out. When
YOU Wenqiang, GUO Jingna, WANG Guanghui
doaj +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The drained triaxial shear tests on isotropic and K0 consolidation of coral sand samples taken from the South China Sea reveal that the consolidation path has a significant effect on the strength characteristics of the coral sand.
HE Shao-heng 1, LIU Zhi-jun 2, XIA Tang-dai 1, ZHOU Hong-xing 2, YU Bing-qi 1
doaj +1 more source
In the dynamic analysis of structural engineering systems, it is common practice to introduce damping models to reproduce experimentally observed features.
Cottereau, Régis, Jehel, Pierre
core +3 more sources
Fatigue crack growth rates for offshore wind monopile weldments in air and seawater: SLIC inter-laboratory test results [PDF]
The majority of fatigue crack growth (FCG) data sets available on steels in air and seawater environments are several decades old and may not be appropriate for structural integrity assessment of offshore wind turbine foundations, which are fabricated ...
Brennan, Feargal P. +2 more
core +2 more sources
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The cyclic loading causes the strength change of porous rocks, which can be frequently encountered in underground coal mining. In order to quantify the cumulative damage of porous coal, multilevel uniaxial cyclic compressive tests were carried out ...
Huajun Wang, Jian Li
doaj +1 more source
Deformation characteristics of saturated remolded loess under cyclic traffic loads
To study the deformation laws of saturated remolded loess under the rotation of principal stress axis, the cyclic triaxial tests and cyclic traffic load tests on the saturated remolded loess under drainage are carried out by using the hollow cylinder ...
WENG Xiao-lin 1, HU Ji-bo 1, JIA Yang 2, ZHOU Shang-qi 1
doaj +1 more source

