Results 61 to 70 of about 332,414 (335)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
International Journal of Technology, 2018 The crack growth behavior of fiber metal laminates (FMLs) with fiber orientations of 90°/0° and 45°/45° to load direction was investigated with varying stress ratios of the cyclic constant load.
Anindito Purnowidodo +3 more
doaj +1 more source
Effect of normal stress on cyclic simple-shear behavior of gravel-structure interface
Rock and Soil Mechanics, 2021 The cyclic simple-shear behavior of soil-structure interfaces under different normal stresses is of great significance in theoretical analysis and engineering practices.
FENG Da-kuo, ZHANG Jian-min
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Effect of grain disorientation on early fatigue crack propagation in face-centred-cubic polycristals: A three-dimensional dislocation dynamics investigation [PDF]
, 2013 Three-dimensional dislocation dynamics simulations are used to study micro-crack interaction with the first micro-structural barrier in face-centred cubic bi-crystals loaded in high cycle fatigue conditions. In the examined configuration, we assumed that
depres, christophe +3 more
core +5 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Advances in Materials Science and Engineering, 2019 The cyclic triaxial system is used to investigate the effects of confining pressure, initial shear stress, cyclic stress ratio, and vibration frequency on the dynamic strength characteristics of saturated sand in the Wenchuan area. Results show that when
Jian Zhang, Jiuting Cao, Sijie Huang
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Soils and Foundations, 2021 This paper presents the findings from an experimental study focusing on the undrained cyclic behavior of sand in the presence of initial static shear stress.
Muhammad Umar +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Experimental Study on Cyclic Simple Shear Test of Coastal Tidal Soft Soil
Journal of Marine Science and EngineeringBased on undrained cyclic simple shear tests conducted on coastal tidal soft soil under various conditions of cyclic stress ratios and moisture contents, this study investigated the influence of these factors on the dynamic properties of the soil.
Xiuxia Yu +4 more
doaj +1 more source
Experimental study on cyclic shear stiffness and damping ratio of carbonate sand-steel interface
Rock and Soil Mechanics, 2020 The dynamic response of carbonate sand-steel interface is of great significance to the safety and stability of the structure foundations which are constructed under reef geotechnical conditions.
RUI Sheng-jie +4 more
doaj +1 more source