Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Mechanistic origin of high-cycle fatigue enhancement by grain refinement in AZ81 magnesium alloy for sports equipment. [PDF]
Li D, He L.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
High-performance flexible electronics from organic fluorosilicone/carbon composites for low-temperature wearable sensors. [PDF]
Ma X, Wang Y, Zhu H.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Design of Conductive Hydrogels Based on the Synergistic Effects of Hydrophobic Frameworks and Dual Antifreeze Strategies, Suitable for Wearable Flexible Sensors. [PDF]
Luo J +6 more
europepmc +1 more source
Comparison of cyclic fatigue properties of four nickel-titanium single-file systems in curved artificial canals. [PDF]
Wang J, Tai Z, Wang X, Han J, Tao J.
europepmc +1 more source
Fracture resistance of regenerated immature teeth in different simulated stages of root development: an in vitro cyclic loading study. [PDF]
Polydora KA +3 more
europepmc +1 more source
Wear, fatigue characteristics, and antibacterial performance of UHMWPE reinforced with HAP+TiO<sub>2</sub> for biomedical applications. [PDF]
Salama A +4 more
europepmc +1 more source

