Results 341 to 350 of about 386,039 (382)
Assays for Cyclin-Dependent Kinase Inhibitors [PDF]
, 2003 Tyler Lahusen, Adrian M. Senderowicz
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2004
The cyclin/cyclin-dependent kinase (Cdk) complexes and the Cdk inhibitors (CDKI) are crucial regulators of cell cycle progression in all eukaryotic cells. Using rat cardiac myocytes as a model system, this chapter provides a detailed account of methods that can be employed to measure both cyclin/Cdk activity in cells and the extent of CDKI inhibitory ...
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The cyclin/cyclin-dependent kinase (Cdk) complexes and the Cdk inhibitors (CDKI) are crucial regulators of cell cycle progression in all eukaryotic cells. Using rat cardiac myocytes as a model system, this chapter provides a detailed account of methods that can be employed to measure both cyclin/Cdk activity in cells and the extent of CDKI inhibitory ...
openaire +3 more sources
Trends in kinase drug discovery: targets, indications and inhibitor design
Nature Reviews Drug Discovery, 2021Helgi B Schiöth +2 more
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Kinase drug discovery 20 years after imatinib: progress and future directions
Nature Reviews Drug Discovery, 2021Darren Cross +2 more
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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
Nature, 2006V. Janzen +9 more
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Kinase inhibition in autoimmunity and inflammation
Nature Reviews Drug Discovery, 2021Ali A Zarrin +2 more
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Lung cancer: New biological insights and recent therapeutic advances
Ca-A Cancer Journal for Clinicians, 2011Suresh S Ramalingam +2 more
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Barata, Brian I Rini
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