Results 181 to 190 of about 109,030,997 (289)

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

Epilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley, Peter Widdess‐Walsh, Christine Linehan, Danielle M. Andrade, Norman Delanty, Patrick B. Moloney   +5 more
wiley   +1 more source

microRNA-769 is Downregulated in Colorectal Cancer and Inhibits Cancer Progression by Directly Targeting Cyclin-Dependent Kinase 1 [Retraction]. [PDF]

Onco Targets Ther, 2021
europepmc   +1 more source

Exploring medical food supplementation as an adjunct strategy for microbiota restoration and seizure reduction in CDKL5 deficiency disorder

Epilepsia Open, EarlyView.
Abstract Objectives CDKL5 deficiency disorder (CDD) is a developmental and epileptic encephalopathy characterized by early‐onset, treatment‐resistant seizures and severe neurodevelopmental impairment. Increasing evidence suggests that alterations in the gut–brain axis may contribute to disease pathophysiology, raising interest in microbiota‐targeted ...
Elisa Borghi, Matteo Domenico Marsiglia, Francesca Triva, Emerenziana Ottaviano, Ilaria Viganò, Miriam Nella Savini, Valentino Costabile, Aglaia Vignoli   +7 more
wiley   +1 more source

Dietary Selenium Supplementation Modulates Proliferative Gene Regulators Through Attenuating Cell Cycle Inhibition on Late G1/S Transition in Pre-Pubertal Goat Testis

Journal of Bioresource Management
Selenium (Se) is essential for normal gonadal improvement in prepubertal male goat. Thus hypothesized that dietary Se may influence late G1/S through M-phase gene networks in the testis, thereby advancing pre-pubertal testicular development via ...
Muhammad Awais Soomro, Moolchand Malhi, Tarique Ahmed Khokhar, Faiz Muhammad Khand, Zafar Ali Khoso, Maria Sardar, Muhammad Mohsen Rahimoon, Awais Bin Shahid, Muhammad Anees Memon, Nabi Bux Solangi, Jawed Ali Dhiloo   +10 more
doaj  

Corrigendum: The Photorhabdus virulence cassettes RRSP-like effector interacts with cyclin-dependent kinase 1 and causes mitotic defects in mammalian cells. [PDF]

Front Microbiol
Wang X, Shen J, Jiang F, Jin Q.
europepmc   +1 more source

Cyclin-Dependent Kinase 1 Is Essential for Muscle Regeneration and Overload Muscle Fiber Hypertrophy. [PDF]

Front Cell Dev Biol, 2020
Kobayashi Y, Tanaka T, Mulati M, Ochi H, Sato S, Kaldis P, Yoshii T, Okawa A, Inose H.   +8 more
europepmc   +1 more source

Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells

Exploration, EarlyView.
Engineered micro/nanomaterials enable high‐efficiency CTC capture, release, and multimodal molecular profiling. Integrated with AI‐driven analytics, these platforms decode tumor heterogeneity and metastatic dynamics, advancing real‐time monitoring and precision oncology through DNA, RNA, and protein cross‐scale data fusion.
Hao Li, Jiaojiao Sun, Kunguo Liu, Shijie Wang, Bowen Fu, Hong Zhu, Peng Cao, Xin Han   +7 more
wiley   +1 more source

Analysis of Cyclin-Dependent Kinase 1 as an Independent Prognostic Factor for Gastric Cancer Based on Statistical Methods. [PDF]

Front Cell Dev Biol, 2020
Zhang X, Ma H, Zou Q, Wu J.
europepmc   +1 more source

Neuroendocrine prostate cancer (NEPC)-associated <i>CEP55</i> promotes cisplatin resistance in prostate cancer by regulating CDK1 phosphorylation. [PDF]

Cancer Pathog Ther
Lai Z, Hu C, Jie J, Xiao Y, Zhu Y, Guo X, Liu Y, Wang Y, Pang S, Zeng X, Tan W, Wang Q.   +11 more
europepmc   +1 more source

Expression patterns and prognostic values of the cyclin-dependent kinase 1 and cyclin A2 gene cluster in pancreatic adenocarcinoma. [PDF]

J Int Med Res, 2020
Jiang P, Zhang M, Gui L, Zhang K.
europepmc   +1 more source