Results 91 to 100 of about 161,781 (188)

A comprehensive view on the fisetin impact on colorectal cancer in animal models: Focusing on cellular and molecular mechanisms

Animal Models and Experimental Medicine
Flavonoids, including fisetin, have been linked to a reduced risk of colorectal cancer (CRC) and have potential therapeutic applications for the condition. Fisetin, a natural flavonoid found in various fruits and vegetables, has shown promise in managing
Mohammad Yasin Zamanian, Niloofar Taheri, Montather F. Ramadan, Yasser Fakri Mustafa, Safa Alkhayyat, Klunko Nataliya Sergeevna, Hashem O. Alsaab, Ahmed Hjazi, Farnoosh Molavi Vasei, Siamak Daneshvar   +9 more
doaj   +1 more source

CENP-F promotes HCC cell proliferation mediated by super enhancer reader BRD4

Discover Oncology
Centromere protein F (CENP-F) is highly expressed in hepatocellular carcinoma (HCC), but the specific mechanism by which it regulates the occurrence and development of HCC is currently unclear.
Yunhui Liu, Wenjiao Chen, Yuxin Niu, Xiaoqin Dong, Jie You, Zhongyuan Yang   +5 more
doaj   +1 more source

The discovery of high affinity and metabolically stable allosteric cyclin-dependent kinase 2 (CDK2) inhibitors from screening through lead optimization [PDF]

, 2022
Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, David J. Burban, H.L.S. Wong, Rawle Francis, Defeng Tian, Kwon Ho Hong, An‐Suei Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas Levinson, E. Schönbrunn, Jon E. Hawkinson, Gunda I. Georg   +16 more
openalex   +1 more source

Human Epidermal Growth Factor Receptor Type 2 (HER2)-Positive Metastatic Breast Cancer With HER2-Negative Conversion: A Case Report and Treatment With Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor for the Luminal Type [PDF]

Ryo Funakushi, Sayaka Kuba, Michi Morita, Momoko Akashi, Susumu Eguchi   +4 more
openalex   +1 more source

Supplementary Figure 3 from Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation [PDF]

, 2023
Nikkí A. Delk, Kelly K. Hunt, Khandan Keyomarsi   +2 more
openalex   +1 more source

Molecular Docking Simulation Studies of Curcumin and Its Derivatives as Cyclin-Dependent Kinase 2 Inhibitors. [PDF]

Turk J Pharm Sci, 2020
Sumirtanurdin R, Sungkar S, Hisprastin Y, Sidharta KD, Nurhikmah DD.   +4 more
europepmc   +1 more source

Analysis of Plant-derived Phytochemicals as Anti-cancer Agents Targeting Cyclin Dependent Kinase-2, Human Topoisomerase IIa and Vascular Endothelial Growth Factor Receptor-2 [PDF]

, 2020
Bishajit Sarkar, Md. Asad Ullah, Syed Sajidul Islam, Md. Hasanur Rahman   +3 more
openalex   +1 more source

Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception†. [PDF]

Biol Reprod, 2020
Faber EB, Wang N, Georg GI.
europepmc   +1 more source

Cell cycle deregulation by the HBx protein of hepatitis B virus

Iatreia, 2007
<p class="MsoNormal"><span style="font-size: 10pt; font-family: QuorumITCbyBT-Book">Cell cycle control by oncogenic viruses usually involves disruption of the normal restraints on cellular proliferation via abnormal proteolytic degradation ...
Vijay Kumar
doaj  

Cyclin-Dependent Kinase-2 Controls Oligodendrocyte Progenitor Cell Cycle Progression and Is Downregulated in Adult Oligodendrocyte Progenitors [PDF]

, 2002
Shibeshih Belachew, Adán Aguirre, Hang Wang, François Vautier, Xiaoqing Yuan, Stacie M. Anderson, Martha Kirby, Vittorio Gallo   +7 more
openalex   +1 more source