Results 121 to 130 of about 161,781 (188)

Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells [PDF]

, 2009
Neil F. Johnson, J. Bentley, L-Z Wang, David R. Newell, Craig Robson, Geoffrey I. Shapiro, Nicola J. Curtin   +6 more
openalex   +1 more source

Supplementary Fig. 2. from Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

, 2023
Alexey V. Danilov, Shanhu Hu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, David Sekula, Xi Liu, Masanori Kawakami, Faye M. Johnson, Duane A. Compton, Sarah J. Freemantle, Ethan Dmitrovsky   +11 more
openalex   +1 more source

Synthesis, docking, MD simulation, ADMET, drug likeness, and DFT studies of novel furo[2,3-b]indol-3a-ol as promising Cyclin-dependent kinase 2 inhibitors. [PDF]

Sci Rep
Gheidari D, Mehrdad M, Bayat M.
europepmc   +1 more source

Supplemental Table 2 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer

, 2023
Seth A. Wander, Ofir Cohen, Xueqian Gong, Gabriela N. Johnson, Jorge E. Buendia-Buendia, Maxwell R. Lloyd, Dewey Kim, Flora Luo, Pingping Mao, Karla Helvie, Kailey J. Kowalski, Utthara Nayar, Adrienne G. Waks, Stephen H. Parsons, Ricardo Martínez, Lacey M. Litchfield, Xiang S. Ye, Chunping Yu, Valerie M. Jansen, John R. Stille, Patricia S. Smith, Gerard J. Oakley, Quincy S. Chu, Gerald Batist, Melissa E. Hughes, Jill D. Kremer, Levi A. Garraway, Eric P. Winer, Sara M. Tolaney, Nancy U. Lin, Sean G. Buchanan, Nikhil Wagle   +31 more
openalex   +1 more source

Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma.

, 2015
由香 石原, ユカ イシハラ, Yuka Ishihara   +2 more
openalex   +1 more source

Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: A QM/MM study. [PDF]

PLoS One, 2019
Recabarren R, Osorio EH, Caballero J, Tuñón I, Alzate-Morales JH.   +4 more
europepmc   +1 more source

Supplementary Figure 2 from ¹⁸F-FLT PET, a Noninvasive Pharmacodynamic Biomarker of Tumor Cell Proliferation, Detected Differential Response to Various Cyclin-Dependent Kinase (CDK) Inhibitors

Anand Giddabasappa, Ziyue Karen Jiang, Bing Yang, Laigao Chen, Feng Liu, Edward Cabral, Sripad Ram, Britton Boras, Nanni Huser, Cathy C. Zhang, Kavon Noorbehesht, Lisa K. Manzuk, Ravi Visswanathan, Sepideh Mojtahedzadeh, Timothy Affolter, Jason Carmody, Aubrey Nayeon Kang, Matthew D. Petroski, Penny Lai Khamphavong, Todd VanArsdale, Quang‐Dé Nguyen, Kevin Maresca, Stephen G. Dann   +22 more
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Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity

, 2006
Xin‐Jie Chu, Wanda DePinto, David Bartkovitz, Sung-Sau So, Binh Thanh Vu, Kathryn Packman, Christine Lukacs, Qingjie Ding, Nan Jiang, Ka Wang, Petra Goelzer, Xuefeng Yin, Melissa Smith, Brian X. Higgins, Yingsi Chen, Qing Xiang, John Moliterni, Gerald L. Kaplan, Bradford Graves, Allen Lovey, Nader Fotouhi   +20 more
openalex   +1 more source

Inhibition of Cyclin-dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury. [PDF]

Transplantation, 2019
Xu J, Xue Z, Zhang C, Liu Y, Busuttil RW, Zhang J, Kupiec-Weglinski JW, Ji H.   +7 more
europepmc   +1 more source

Supplementary Figure 2 from Combined Depletion of Cell Cycle and Transcriptional Cyclin-Dependent Kinase Activities Induces Apoptosis in Cancer Cells

, 2023
Dongpo Cai, Vaughan M. Latham, Xinxin Zhang, Geoffrey I. Shapiro   +3 more
openalex   +1 more source