Results 161 to 170 of about 543,132 (243)
Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia
Exploration, EarlyView.We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley +1 more source
Novel Role for Cyclin-dependent Kinase 2 in Neuregulin-induced Acetylcholine Receptor ϵ Subunit Expression in Differentiated Myotubes [PDF]
, 2005 Gang Lü +2 more
openalex +1 more source
Delivery of Natural Small Molecules Through Nanocarriers for Cancer Treatment
Food Frontiers, EarlyView.Natural small molecules through nanocarriers for cancer treatment ABSTRACT Cancer is a formidable adversary, accounting for the second highest number of fatalities worldwide. A multitude of studies have indicated that naturally sourced small‐molecule compounds, owing to their low toxicity and multi‐target capabilities, significantly aid in the fight ...
Fangting Ye +7 more
wiley +1 more source
Molecular Motions of Human Cyclin-dependent Kinase 2 [PDF]
, 2005 C. Paul Barrett, M.E.M. Noble
openalex +1 more source
Food Frontiers, EarlyView.Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno +17 more
wiley +1 more source
Interferon γ Induces Neurite Outgrowth by Up-regulation of p35 Neuron-specific Cyclin-dependent Kinase 5 Activator via Activation of ERK1/2 Pathway [PDF]
, 2005 Jin H. Song +5 more
openalex +1 more source
Head &Neck, Volume 47, Issue 6, Page 1726-1735, June 2025.ABSTRACT Background The detection rate of oncogenic human papillomaviruses (HPVs) in sinonasal squamous cell carcinomas (SNSCCs) varies among studies. The mutational landscape of SNSCCs remains poorly investigated. Methods We investigated the prevalence and prognostic significance of HPV infections based on p16 protein expression, HPV‐DNA detection ...
Maxime Henrion +8 more
wiley +1 more source
A Simple and Efficient Docking Method to the Cyclin-Dependent Kinase 2 [PDF]
, 2007 Kwang‐Su Park +3 more
openalex +1 more source