Results 31 to 40 of about 152,744 (302)
Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma. [PDF]
Cancer Sci, 2019 Hepatocellular carcinoma (HCC) is a common and aggressive malignant tumor with a poorly defined molecular mechanism. Cyclin‐dependent kinase 2 (CDK2) and Septin2 (SEPT2) are 2 known oncogenic molecules but the mechanism of functional interactions remains unclear.
Xu C +10 more
europepmc +5 more sources
Wound Healing Potential of Spirulina Protein on CCD-986sk Cells
Marine Drugs, 2019 Wound healing is a dynamic and complex process. The proliferation and migration of dermal fibroblasts are crucial for wound healing. Recent studies have indicated that the extracts from Spirulina platensis have a positive potential for wound healing ...
Ping Liu +4 more
doaj +1 more source
Cell Death and Disease, 2023 Esophageal squamous cell carcinoma (ESCC) is an upper gastrointestinal cancer with high morbidity and mortality. New strategies are urgently needed to prolong patients’ survival.
Xinning Liu +12 more
doaj +1 more source
Cells, 2021 Targeting the activities of endoplasmic reticulum (ER)–mitochondrial-dependent metabolic reprogramming is considered one of the most promising strategies for cancer treatment. Here, we present biochemical subcellular fractionation, coimmunoprecipitation,
Jan-Gowth Chang +4 more
doaj +1 more source
CCL21/CCR7 promotes G2/M phase progression via the ERK pathway in human non-small cell lung cancer cells. [PDF]
PLoS ONE, 2011 C-C chemokine receptor 7 (CCR7) contributes to the survival of certain cancer cell lines, but its role in the proliferation of human non-small cell lung cancer (NSCLC) cells remains vague. Proliferation assays performed on A549 and H460 NSCLC cells using
Ying Xu +8 more
doaj +1 more source
A multi-centre study on the role of the thioredoxin system in breast cancer cell proliferation
Бюллетень сибирской медицины, 2018 Redox proteins (thioredoxin, glutaredoxin) are key macromolecules capable of modulating intracellular processes. This determines research choices in the field of redox-dependent cell proliferation management.
E. V. Shakhristova +7 more
doaj +1 more source
Cyclin-Dependent Kinase-2 in the Birth and Death of Cardiac Muscle Cells [PDF]
Circulation Research, 2001 The proliferative cell cycle in both vertebrates and much simpler organisms entails the transduction of mitogenic signals to cyclically expressed proteins known as cyclins and, hence, to their catalytically active targets, the cyclin-dependent protein kinases (cdks).1 2 In yeast, a single kinase, cdc28, suffices to partner with all of the cyclins ...
W. Robb MacLellan, Michael D. Schneider
openaire +3 more sources
Direct Activation of Cyclin-Dependent Kinase 2 by Human Papillomavirus E7 [PDF]
Journal of Virology, 2003 ABSTRACT Addition of human papillomavirus (HPV) E7 CDK2/cyclin A or CDK2/cyclin E, purified from either insect cells or bacteria, dramatically upregulates histone H1 kinase activity. Activation is substrate specific, with a smaller effect noted for retinoblastoma protein (Rb). The CDK2 stimulatory activity is equivalent in high-risk (HPV type
Chris Fisher +3 more
openaire +3 more sources
Cervical Liposarcoma Revisited: A Case Report and Scoping Literature Review
Case Reports in Oncology, 2022 The commonest sites for liposarcoma are the retroperitoneum and lower extremities. Liposarcoma of the head and neck region is a rare and potentially life-threatening malignancy.
Takahiro Suzuki +9 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2022 Cyclin-dependent kinase 9 (CDK9) activity is correlated with worse outcomes of triple-negative breast cancer (TNBC) patients. The heterodimer between CDK9 with cyclin T1 is essential for maintaining the active state of the kinase and targeting this ...
Sha-Sha Cheng +12 more
doaj