Results 181 to 190 of about 338,209 (343)

Dietary Glutamine Supplementation Alleviated Rumen Epithelium Oxidative Damage and Apoptosis Induced by Feed Restriction via Maintaining Mitochondrial Homeostasis in Female Yaks

Animal Research and One Health, EarlyView.
Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue, Shanpeng Ke, Liyuan Shi, Rui Hu, Zhisheng Wang, Quanhui Peng, Huawei Zou, Jianxin Xiao, Yahui Jiang, Fali Wu, Yiping Tang   +10 more
wiley   +1 more source

Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery. [PDF]

Antioxidants (Basel), 2023
Ishii T, Warabi E, Mann GE.
europepmc   +1 more source

Up-regulation of microRNA-21 correlates with lower kidney cancer survival. [PDF]

, 1929
BackgroundMicroRNA-21 is up-regulated in a variety of cancers like, breast, colorectal, lung, head and neck etc. However, the regulation of miR-21 in renal cell carcinoma (RCC) has not yet been studied systematically.Methods and resultsWe measured miR-21
Zaman, Mohd Saif, Shahryari, Varahram, Deng, Guoren, Thamminana, Sobha, Saini, Sharonjot, Majid, Shahana, Chang, Inik, Hirata, Hiroshi, Ueno, Koji, Yamamura, Soichiro, Singh, Kamaldeep, Tanaka, Yuichiro, Tabatabai, Z Laura, Dahiya, Rajvir   +13 more
core  

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Nobiletin mitigates benign prostatic hyperplasia by suppressing prostate cell proliferation through regulation of cell cycle progression, signaling pathways, transcription factor activity, and the androgen-signaling axis

Frontiers in Pharmacology
Background and aimBenign prostatic hyperplasia (BPH) involves androgen-driven proliferation with reduced apoptosis. Current 5α-reductase inhibitors can cause adverse effects, motivating safer options.
Jun-Hui Song, Daeun Lee, Byungdoo Hwang, Seon-Kyung Hwang, Sumin Choo, Hyeon Ji Jeong, Hoon Kim, Byungyoon Cha, Seok-Joong Yun, Yung Hyun Choi, Wun-Jae Kim, Wun-Jae Kim, Sung-Kwon Moon   +12 more
doaj   +1 more source

Role of cyclin-dependent kinase 5 in early brain injury following experimental subarachnoid hemorrhage. [PDF]

Exp Ther Med, 2022
Ding Y, Zhang L, Zhou W, Lu H, Gao X, Li J, Liu J, Niu X, Zheng J.   +8 more
europepmc   +1 more source

Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]

, 2008
De Mattia, Roberta
core   +1 more source

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

Proceedings of the National Academy of Sciences of the United States of America, 1996
T. Ohshima, Jerrold M. Ward, C. Huh, G. Longenecker, Veeranna, H. Pant, R. Brady, L. Martin, A. Kulkarni   +8 more
semanticscholar   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

British Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel, Adeline Benis, Philippe Bonniaud, Jean‐Luc Faillie, Aurélie Grandvuillemin   +4 more
wiley   +1 more source

Cyclin dependent kinase 5 (CDK5) [PDF]

Science-Business eXchange, 2010
openaire   +2 more sources