G1–checkpoint Function Including a Cyclin‐dependent Kinase 2 Regulatory Pathway as Potential Determinant of 7–Hydroxystaurosporine (UCN‐01)‐induced Apoptosis and G1–phase Accumulation [PDF]
Tadakazu Akiyama+4 more
openalex +1 more source
Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
P. Hydbring+2 more
semanticscholar +1 more source
Risk of Cardiovascular Events with Cyclin-Dependent Kinases 4 and 6 (CDK 4/6) Inhibitors among Patients with Advanced Breast Cancer: A Systematic Review and Network Meta-Analysis. [PDF]
Liu YS, Dong K, Park C.
europepmc +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source
Transcription associated cyclin-dependent kinases as therapeutic targets for prostate cancer. [PDF]
Constantin TA+3 more
europepmc +1 more source
The Novel Cyclin-Dependent Kinase Inhibitor Flavopiridol Downregulates Bcl-2 and Induces Growth Arrest and Apoptosis in Chronic B-Cell Leukemia Lines [PDF]
Andrea König+4 more
openalex +1 more source
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen+11 more
wiley +1 more source
Comprehensive Analysis of Role of Cyclin-Dependent Kinases Family Members in Colorectal Cancer. [PDF]
Guan L, Tang Y, Li G, Qin Z, Li S.
europepmc +1 more source
Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]
De Mattia, Roberta
core +1 more source