Results 211 to 220 of about 382,305 (392)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

When cyclin-dependent kinases meet viral infections, including SARS-CoV-2. [PDF]

J Med Virol, 2022
Yan Y, Tang YD, Zheng C.
europepmc   +1 more source

Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

, 1997
Béatrice Durand
openalex   +2 more sources

Preliminary crysallization of a cyclin-dependent kinase inhibitor: P18 [PDF]

, 1996
S. Jarchow, Hengming Ke
openalex   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation. [PDF]

Sci Rep, 2023
Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, Zhang K, Bienkowska J, Mali P, Ideker T.   +18 more
europepmc   +1 more source

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27Kip1 [PDF]

, 1999
Keiju Hiromura, Jeffrey W. Pippin, Matthew L. Fero, James M. Roberts, Stuart J. Shankland   +4 more
openalex   +1 more source

Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential

Chemistry &Biodiversity, EarlyView.
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira, Milena F. Longue, Letícia M. R. Pescinelli, Thiago S. Charret, Thalya S. R. Nogueira, Mariana T. M. Pereira, Ivo J. C. Vieira, Lucas S. Abreu, Vinicius D. B. Pascoal, Aislan C. R. F. Pascoal   +9 more
wiley   +1 more source

Clinicopathological value of the upregulation of cyclin-dependent kinases regulatory subunit 2 in osteosarcoma. [PDF]

BMC Med Genomics, 2022
Mo C, Wu Y, Ma J, Xie L, Huang Y, Xu Y, Peng H, Chen Z, Zeng M, Mao R.   +9 more
europepmc   +1 more source

Inhibitors of cyclin‐dependent kinases as cancer therapeutics

Pharmacology and Therapeutics, 2017
S. Whittaker, A. Mallinger, P. Workman, P. Clarke   +3 more
semanticscholar   +1 more source