Results 281 to 290 of about 382,305 (392)
What's New? Multiple genetic polymorphisms characteristic of type 2 diabetes (T2D) have been associated with unfavorable prognostic outcomes in individuals with both T2D and metastatic colorectal cancer. This study evaluated the impact of T2D genetic polymorphisms on metastatic colon cancer prognosis in a cohort of non‐diabetic patients.
Raffaella Ruggiero+11 more
wiley +1 more source
Genetic Status and Expression of the Cyclin‐dependent Kinase Inhibitors in Human Gastric Carcinoma Cell Lines [PDF]
Yoshihiko Akama+7 more
openalex +1 more source
Diagnosis and management of gestational trophoblastic disease: 2025 update
Abstract Gestational trophoblastic disease (GTD) arises from abnormal placenta and comprises a spectrum of premalignant to malignant disorders. Changes in the epidemiology of GTD have been noted in various countries. In addition to histology, molecular genetic studies can help in the diagnostic pathway.
Hextan Y. S. Ngan+7 more
wiley +1 more source
Prostaglandin A2 Blocks the Activation of G1 Phase Cyclin-dependent Kinase without Altering Mitogen-activated Protein Kinase Stimulation [PDF]
Masahiro Hitomi+5 more
openalex +1 more source
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]
Cascales, H.S.+4 more
core +3 more sources
Current Progress in Targeting Human Cytomegalovirus Infection
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley +1 more source
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
wiley +1 more source
Expression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma
C. Abdullah, Xiaolei Wang, D. Becker
semanticscholar +1 more source
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source