Results 131 to 140 of about 45,816 (242)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

open access: yesCell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu   +5 more
wiley   +1 more source

Screening for Potential Biomarkers in Peripheral Blood From Miners Exposed to Radon Radiation

open access: yesDose-Response, 2020
In this cohort study of 144 miners, 72 miners worked underground (the study group) and 72 miners worked aboveground (the control group). Based on questionnaire data and of radon concentration measurements, the cumulative radon exposure dose was ...
Lu Sun   +7 more
doaj   +1 more source

The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]

open access: yes, 2008
We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens   +9 more
core   +1 more source

Bifurcation analysis of a model of the budding yeast cell cycle

open access: yes, 2004
We study the bifurcations of a set of nine nonlinear ordinary differential equations that describe the regulation of the cyclin-dependent kinase that triggers DNA synthesis and mitosis in the budding yeast, Saccharomyces cerevisiae.
Battogtokh, Dorjsuren, Tyson, John J.
core   +1 more source

Supplementary Figure 8 from Loss of Cdk2 and Cyclin A2 Impairs Cell Proliferation and Tumorigenesis [PDF]

open access: gold, 2023
Lakshmi Gopinathan   +5 more
openalex   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Supplementary Tables 1 and 2 from Attenuation of Argininosuccinate Lyase Inhibits Cancer Growth via Cyclin A2 and Nitric Oxide [PDF]

open access: gold, 2023
Hau-Lun Huang   +9 more
openalex   +2 more sources

A single‐MYB transcription factor GmMYB331 regulates seed oil accumulation and seed size/weight in soybean

open access: yesJournal of Integrative Plant Biology, EarlyView.
The soybean transcription factor GmMYB331 regulates oil content and seed size. Moderate expression of GmMYB331 significantly enhanced seed oil accumulation, and strong expression promoted increased seed size. This research provides a genetic resource and theoretical foundation for high‐yield and quality breeding in soybean.
Zhou‐Ya Wang   +11 more
wiley   +1 more source

Identification of Arabidopsis meiotic cyclins reveals functional diversification among plant cyclin genes.

open access: yesPLoS Genetics, 2013
Meiosis is a modified cell division in which a single S-phase is followed by two rounds of chromosome segregation resulting in the production of haploid gametes.
Petra Bulankova   +3 more
doaj   +1 more source

Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network [PDF]

open access: yes, 2010
As in other eukaryotes, cell division in plants is highly conserved and regulated by cyclin-dependent kinases (CDKs) that are themselves predominantly regulated at the posttranscriptional level by their association with proteins such as cyclins. Although
Boruc, Joanna   +8 more
core   +4 more sources

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