Results 191 to 200 of about 45,816 (242)

NSD3S Promotes Cell Proliferation Through Stabilizing c‐Myc in Psoriatic Keratinocytes

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Histone methyltransferase nuclear receptor binding SET domain protein 3 (NSD3) has been reported to promote cell proliferation in a variety of cancer cells. However, whether NSD3 regulates cell proliferation in psoriatic cells is unknown. Here, we found elevated expression of NSD3S (the short isoform with no activity) but not NSD3L (the long isoform ...
Jinglin Xiong, Maomao Yan, Jiawen Yin, Min Xu, Xianzhong Zhu, Qing Qi, Wenlin Yang, Suraiya Saleem   +7 more
wiley   +1 more source

Combined treatment with CDK4/6, CDK2, and CXCR1/2 inhibitors effectively halts the growth of BRAF wild-type melanoma tumors

Frontiers in Oncology
IntroductionInhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) are approved for the treatment of locally advanced or metastatic breast cancer, but not for melanoma.MethodsIn this study, we evaluated the effectiveness of the CDK4/6 inhibitor ...
Jinming Yang, Jinming Yang, Weifeng Luo, Weifeng Luo, Patricia Ward, Sheau-Chiann Chen, John Zebala, Dean Maeda, Chi Yan, Chi Yan, Chi Yan, Chi Yan, Ann Richmond, Ann Richmond   +13 more
doaj   +1 more source

HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. [PDF]

, 2019
Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation.
Chen, Yifang, Harismendy, Olivier, Jones, Jackson, Li, Jingting, Ling, Ji, Sen, George L, Tiwari, Manisha, Wang, Ying, Xu, Xiaojun   +8 more
core   +1 more source

The Traditional Chinese Medicine Compound Hezi Qingyou Formula Controls the MAPK Signaling Pathway for Alleviating Gastric Ulcer Induced by Acetic Acid in Rats

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
In clinical practice, Hezi Qingyou Formula (HZQYF) has been observed to effectively alleviate clinical symptoms associated with gastri ulcers, though its precise mechanism of action remains unclear. To investigate the effects of HZQYF on gastric ulcers, we established a rat model of gastric ulcer and examined its impact on ulcer area, pathological ...
Zhong Feng, Ruixia Wei, Junhao Tian, Hui Li, Haobo Chen, Yajie Hao, Meiyun Chen, Bingmei Su, Yuqian Lai, Mingjin Xun, Guimin Zhang, Meicun Yao, Poorani Gurumallesh   +12 more
wiley   +1 more source

Cyclin A2 Induces Cytokinesis in Human Adult Cardiomyocyte and Drives Reprogramming in Mice [PDF]

Esmaa Bouhamida, Sangeetha Vadakke‐Madathil, Prabhu Mathiyalagan, Amaresh K. Ranjan, Cherrie D. Sherman, Paul E. Miller, Andre Ghetti, Najah Abi‐Gerges, Hina W. Chaudhry, Hina W. Chaudhry   +9 more
openalex   +1 more source

TheMedicagoSpecies A2-Type Cyclin Is Auxin Regulated and Involved in Meristem Formation But Dispensable for Endoreduplication-Associated Developmental Programs [PDF]

, 2003
François Roudier, Elena Fedorova, Manuel Lebris, Phillippe Lecomte, János Györgyey, D. Vaubert, Gábor Horväth, Pierre Abad, Ádám Kondorosi, Éva Kondorosi   +9 more
openalex   +1 more source

Expression patterns and prognostic values of the cyclin-dependent kinase 1 and cyclin A2 gene cluster in pancreatic adenocarcinoma. [PDF]

J Int Med Res, 2020
Jiang P, Zhang M, Gui L, Zhang K.
europepmc   +1 more source

Supplementary Figure 4 from Attenuation of Argininosuccinate Lyase Inhibits Cancer Growth via Cyclin A2 and Nitric Oxide

, 2023
Hau-Lun Huang, Hui‐Ping Hsu, Shu-Chu Shieh, Yung‐Sheng Chang, Wei-Ching Chen, Chien-Yu Cho, Chiao‐Fang Teng, Ih‐Jen Su, Wen‐Chun Hung, Ming‐Derg Lai   +9 more
openalex   +1 more source

Endometrial cyclin A2 deficiency is associated with human female infertility and is recapitulated in a conditional knockout mouse model [PDF]

, 2023
Fatimah Aljubran, Katelyn Shumacher, Amanda Graham, Sumedha Gunewardena, Courtney Marsh, Michael Lydic, Kristin Holoch, Warren B. Nothnick   +7 more
openalex   +1 more source

Supplementary Figure 6 from Loss of Cdk2 and Cyclin A2 Impairs Cell Proliferation and Tumorigenesis

, 2023
Lakshmi Gopinathan, Shawn Lu Wen Tan, V. C. Padmakumar, Vincenzo Coppola, Lino Tessarollo, Philipp Kaldis   +5 more
openalex   +1 more source