Long non-coding RNAs HERH-1 and HERH-4 facilitate cyclin A2 expression and accelerate cell cycle progression in advanced hepatocellular carcinoma. [PDF]
BMC Cancer, 2021 Liu T +9 more
europepmc +3 more sources
Myocardial regeneration therapy for ischemic cardiomyopathy with cyclin A2 [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2007 Heart failure therapies ranging from revascularization to remodeling to replacement are variably effective. Theoretically, endogenous repair via myocardial regeneration would be an ideal therapy. This study examined the ability to initiate regeneration by adenoviral-mediated expression of the cell cycle regulator cyclin A2.
Y. Joseph Woo +6 more
openalex +3 more sources
Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6 [PDF]
Scientific Reports, 2017 Although we have shown that avian reovirus (ARV) p17-mediated inhibition of Akt leads to induction of autophagy, the precise mechanisms remain largely unknown.
Wei-Ru Huang +6 more
doaj +2 more sources
<i>Herba Patriniae</i> Component Linarin Induces Cell Cycle Arrest and Senescence in Non-Small-Cell Lung Cancer Associated with Cyclin A2 Downregulation. [PDF]
Pharmaceuticals (Basel)Xie W +6 more
europepmc +3 more sources
Cyclin A2 is essential for mouse gonocyte maturation. [PDF]
Cell Cycle, 2020 In mammals, male gonocytes are derived from primordial germ cells during embryogenesis, enter a period of mitotic proliferation, and then become quiescent until birth. After birth, the gonocytes proliferate and migrate from the center of testicular cord toward the basement membrane to form the pool of spermatogonial stem cells (SSCs) and establish the ...
Ma F +5 more
europepmc +4 more sources
The microRNAs miR-449a and miR-424 suppress osteosarcoma by targeting cyclin A2 expression. [PDF]
J Biol Chem, 2019 Shekhar R +6 more
europepmc +3 more sources
Differential expression of cyclin A2 in triple negative breast cancer.
, 2021 Women diagnosed with triple negative breast cancer can benefit neither from endocrine therapy nor from HER2-targeted therapies (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer.
Shahan Mamoor
openalex +3 more sources
ESRP1 Induces Cervical Cancer Cell G1-Phase Arrest Via Regulating Cyclin A2 mRNA Stability. [PDF]
Int J Mol Sci, 2019 Chen ZH +6 more
europepmc +3 more sources
Cyclin A2 regulates erythrocyte morphology and numbers. [PDF]
Cell Cycle, 2016 Cyclin A2 is an essential gene for development and in haematopoietic stem cells and therefore its functions in definitive erythropoiesis have not been investigated. We have ablated cyclin A2 in committed erythroid progenitors in vivo using erythropoietin receptor promoter-driven Cre, which revealed its critical role in regulating erythrocyte morphology
Jayapal SR +10 more
europepmc +4 more sources