Results 41 to 50 of about 19,762 (141)
Posttranscriptional Regulation of Cyclin A1 and Cyclin A2 During Mouse Oocyte Meiotic Maturation and Preimplantation Development1 [PDF]
Biology of Reproduction, 2001 A shift from a meiotic cell cycle to a mitotic cell cycle occurs following fertilization. The molecular basis for this transition, however, is poorly understood. Although cyclin A1 is proposed to regulate M phase in the meiotic cell cycle, and cyclin A2 is proposed to regulate S and M phases in the mitotic cell cycle, little is known about changes in ...
Daiichiro Fuchimoto +4 more
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UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis
Molecular Biology of the Cell, 2012 Ubiquitin-like, containing PHD and RING finger domains 1 (uhrf1) is regulated at the transcriptional level during the cell cycle and in developing zebrafish embryos. We identify phosphorylation as a novel means of regulating UHRF1 and demonstrate that Uhrf1 phosphorylation is required for gastrulation in zebrafish.
Jaime Chu +10 more
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Differential phosphorylation patterns between the Cyclin-A2/CDK2 complex and their monomers [PDF]
Protein Expression and Purification, 2009 The Cyclin-A2/CDK2 is a protein heterodimer with kinase activity that plays a key role in centrosome duplication and meiotic cell division. To check the suitability of the insect cells for the production and characterization of phosphorylated mammalian proteins, both proteins were expressed individually or as a complex using the baculovirus expression ...
Casado-Vela, Juan +2 more
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Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation [PDF]
, 2018 p27$^{Kip1}$ (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)$/$cyclin complexes (e.g., Cdk2$/$cyclin A), inhibiting their catalytic activity and causing cell cycle arrest. However, cell division progresses when stably Cdk2$/$cyclin A-bound p27 is phosphorylated on one or two structurally ...
arxiv +1 more source
A2: Mathematical relativity and other progress in classical gravity theory - a session report [PDF]
Gen Relativ Gravit (2014) 46:1695, 2013 We report on selected oral contributions to the A2 session "Mathematical relativity and other progress in classical gravity theory" of "The 20th International Conference on General Relativity and Gravitation (GR20)" in Warsaw.
arxiv +1 more source
Separation of variables for A2 Ruijsenaars model and new integral representation for A2 Macdonald polynomials [PDF]
J.Phys.A29:2779-2804,1996, 1996 Using the Baker-Akhiezer function technique we construct a separation of variables for the classical trigonometric 3-particle Ruijsenaars model (relativistic generalization of Calogero-Moser-Sutherland model). In the quantum case, an integral operator M is constructed from the Askey-Wilson contour integral.
arxiv +1 more source
The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events [PDF]
Molecular Biology of the Cell, 2010 Here we have used siRNAs and time-lapse epifluorescence microscopy to examine the roles of various candidate mitotic cyclins in chromatin condensation in HeLa cells. Knocking down cyclin A2 resulted in a substantial (∼7 h) delay in chromatin condensation and histone H3 phosphorylation, and expressing an siRNA-resistant form of cyclin A2 partially ...
Delquin Gong, James E. Ferrell
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Role of Cyclin A2 In Aging Hippocampus And rRna Dynamics
The FASEB Journal, 2018 BackgroundNovel functions of cyclin A2 (CCNA2) have been demonstrated including DNA synthesis initiation and progression, DNA repair, and protein translation through RNA binding. Previously, we reported that loss of CCNA2 leads to hippocampal defects characterized by abnormal DNA repair and impaired performance on behavioral tests due to memory and ...
Samara Mendez Nunez +7 more
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From sound to meaning in the auditory cortex: A neuronal representation and classification analysis [PDF]
arXiv, 2023 The neural mechanisms underlying the comprehension of meaningful sounds are yet to be fully understood. While previous research has shown that the auditory cortex can classify auditory stimuli into distinct semantic categories, the specific contributions of the primary (A1) and the secondary auditory cortex (A2) to this process are not well understood.
arxiv
P/2010 A2 LINEAR II: dynamical dust modelling [PDF]
, 2012 P/2010 A2 is an object on an asteroidal orbit that was observed to have an extended tail or debris trail in January 2010. In this work, we fit the outburst of P/2010 A2 with a conical burst model, and verify previous suspicions that this was a one--time collisional event rather than an sustained cometary outburst, implying that P/2010 A2 is not a new ...
arxiv +1 more source