Results 181 to 190 of about 592,070 (354)
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi+8 more
wiley +1 more source
On optimality of designs with three distinct eigenvalues [PDF]
Let $\D_{v,b,k}$ denote the family of all connected block designs with $v$ treatments and $b$ blocks of size $k$. Let $d\in\D_{v,b,k}$. The replication of a treatment is the number of times it appears in the blocks of $d$. The matrix $C(d)=R(d)-\frac{1}{k}N(d)N(d)^\top$ is called the information matrix of $d$ where $N(d)$ is the incidence matrix of $d$
arxiv
Cyclin A/CDK2 Regulates V(D)J Recombination by Coordinating RAG-2 Accumulation and DNA Repair [PDF]
Jinhak Lee, Stephen Desiderio
openalex +1 more source
Expression of Concern for Patel et al., "Brk/Protein Tyrosine Kinase 6 Phosphorylates p27KIP1, Regulating the Activity of Cyclin D-Cyclin-Dependent Kinase 4". [PDF]
American Society for Microbiology.
europepmc +1 more source
This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai+9 more
wiley +1 more source
On the automorphism groups of algebraic bounded domains [PDF]
Let $D$ be a bounded domain in $C^n$. By the theorem of H.~Cartan, the group $Aut(D)$ of all biholomorphic automorphisms of $D$ has a unique structure of a real Lie group such that the action $Aut(D)\times D\to D$ is real analytic. This structure is defined by the embedding $C_v\colon Aut(D)\hookrightarrow D\times Gl_n(C)$, $f\mapsto (f(v), f_{*v ...
arxiv
Expression of cyclins A and D and p21(waf1/cip1) proteins in renal cell cancer and their relation to clinicopathological variables and patient survival [PDF]
S. Aaltomaa+5 more
openalex +1 more source
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. [PDF]
Maiani E+45 more
europepmc +1 more source
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin+3 more
wiley +1 more source
Regulation of the catalytic subunit (p34PSK-J3/cdk4) for the major D-type cyclin in mature B lymphocytes. [PDF]
Debra A. Tanguay, Thomas C. Chiles
openalex +1 more source