Crystal structure of human CDK4 in complex with a D-type cyclin
Philip J. Day+10 more
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The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma. [PDF]
Stein CK+16 more
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Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta). [PDF]
Fukuda T+13 more
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Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D. [PDF]
Pauklin S+3 more
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Co-expressed Cyclin D variants cooperate to regulate proliferation of germline nuclei in a syncytium. [PDF]
Subramaniam G+2 more
europepmc +1 more source
Plasticity of mitotic cyclins in promoting the G2-M transition. [PDF]
Crncec A+7 more
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Simultaneous cyclin D1 overexpression and p27<sup>kip1</sup> knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina. [PDF]
Wu Z+6 more
europepmc +1 more source
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CRL4AMBRA1 is a master regulator of D-type cyclins
Nature, 2021D-type cyclins are central regulators of the cell division cycle and are among the most frequently deregulated therapeutic targets in human cancer1, but the mechanisms that regulate their turnover are still being debated2,3. Here, by combining biochemical and genetics studies in somatic cells, we identify CRL4AMBRA1 (also known as CRL4DCAF3) as the ...
Valentina Cianfanelli+22 more
openaire +5 more sources