Results 171 to 180 of about 622,161 (318)
Marketing action to promote cycling.
, 2013 Today marketing actions are instruments in the toolbox of cycling promotion that have proven successful in selling everything around cycling through creative and targeted measures. Bike actions can emotionalise cycling. They can reach new target groups
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The reliability of performance during computer-simulated varying gradient cycling time trials
, 2014 Ergometer based time trials are commonly used to assess performance changes due to training or other interventions. This investigation establishes the reliability of a novel computer simulated cycling time trial.
Clark, Bradley +4 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Encouraging cycling in rural municipalities.
, 2018 Compared to big cities, rural areas pose different and greater challenges when it comes to cycling promotion. The different stakeholders have different responsibilities and thus a large amount of coordination is needed.
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Weight cycling and cancer risk in the Sister Study. [PDF]
Am J EpidemiolStevens VL +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Uni-cycle: universities fostering a culture of cycling
, 2008 Published in Thinking on Two Wheels Cycling Conference, 2005-2007 / Stuart Clement (ed.): p ...
Bonham, J., Koth, B.
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The Effect of CYP1A2 Gene Polymorphisms on Caffeine Pharmacokinetics and Exercise Performance in Male Recreational Athletes. [PDF]
Eur J Sport SciMasters C +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source