Results 61 to 70 of about 4,205,053 (351)

Cycling on the Verge? Exploring the Place of Utility Cycling in Contemporary New Zealand Transport Policy [PDF]

, 2014
Efforts to increase cycling as a mode of transport (utility cycling) occur at central, regional and local levels of government through a range of supportive strategies, research, and guidelines.
Smith, Megan
core  

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Changes in continental weathering regimes inhibited global marine deoxygenation during the Paleocene-Eocene thermal maximum

Nature Communications
The moderate impact of rapid global warming on oceanic redox and biodiversity during the Paleocene-Eocene thermal maximum (PETM; ~55.9 Ma) contrasts with other hyperthermal events in Earth’s history, and remains mostly unexplained.
Guang-Yi Wei, Alexandre Pohl, Shijun Jiang, Hua Zhang, Wenqian Wang, Philip A. E. Pogge von Strandmann, Pierre Maffre, Guolin Xiong, Shu-zhong Shen, Feifei Zhang   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Potassium Isotope Evidence for Origin of Archean TTG Rocks From Seawater‐Hydrothermally Altered Oceanic Crust

Geochemistry, Geophysics, Geosystems
Tonalite‐trondhjemite‐granodiorite (TTG) rocks constitute a crucial part of the Archean continental crust, yet their origins remain contentious. It is critical to decipher their source nature and hydration mechanism.
D.‐Y. Xiong, X.‐L. Wang, W. Li, Y.‐F. Zheng, C. R. Anhaeusser, A. Hofmann, D. Wang, J.‐Y. Li   +7 more
doaj   +1 more source

Collaboration, experimentation, continuous improvement: Exploring an iterative way of working in the Municipality of Amsterdam’s Bicycle Program

Transportation Research Interdisciplinary Perspectives, 2021
As demand for cycling rises, cities are scaling up their bicycle planning and infrastructure efforts. There is not only a knowledge gap to building this infrastructure, but also an organizational learning gap, as planning organizations are stepping into ...
Trey Hahn, Marco te Brömmelstroet
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Super-resolution reconstruction, recognition, and evaluation of laser confocal images of hyperaccumulator Solanum nigrum endocytosis vesicles based on deep learning: Comparative study of SRGAN and SRResNet

Frontiers in Plant Science, 2023
It is difficult for laser scanning confocal microscopy to obtain high- or ultra-high-resolution laser confocal images directly, which affects the deep mining and use of the embedded information in laser confocal images and forms a technical bottleneck in
Wenhao Li, Ding He, Yongqiang Liu, Fenghe Wang, Fengliang Huang   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Comparison of stimulation patterns for FES-cycling using measures of oxygen cost and stimulation cost [PDF]

, 2006
<b>Aim</b><p></p> The energy efficiency of FES-cycling in spinal cord injured subjects is very much lower than that of normal cycling, and efficiency is dependent upon the parameters of muscle stimulation.
Stone, B., Grant, S., Hunt, K.J., Fraser, M.H., Allen, D.B., Ferrario, C., McLean, A.N.   +6 more
core   +1 more source