Results 111 to 120 of about 2,643,362 (304)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Relationship Between Cycling Mechanics and Core Stability

open access: yesThe Journal of Strength and Conditioning Research, 2007
Core stability has received considerable attention with regards to functional training in sports. Core stability provides the foundation from which power is generated in cycling. No research has described the relationship between core stability and cycling mechanics of the lower extremity.
John P, Abt   +5 more
openaire   +2 more sources

The metabolic cost of balance in cycling

open access: yes, 2013
Ergometers and stationary bicycle trainers are commonly used in laboratories to simulate overground riding. Missing from such instrumentation, however, is any demand for balance and the fraction of the metabolic cost associated with dynamic balance.
Smith, Gerald A   +3 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Sustained and Efficient Ethanol Oxidation by Tethering Tunable N‐Donors Onto Integrated MXene/Pd‐Electrodes

open access: yesAdvanced Science
The practical development of ethanol fuel cells as a future energy technology is currently set back by fundamental roadblocks (low cycling stability) and design shortcomings, e.g., poorly‐defined active sites and underexplored electrode integration ...
Zhangxin Chen   +11 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Oral β-hydroxybutyrate salt fails to improve 4-minute cycling performance following submaximal exercise [PDF]

open access: yes, 2017
The purpose of the present study was to examine the effects of an oral β-hydroxybutyrate (BHB) supplement on cycling performance. Using a double-blind, placebo-controlled, crossover design, 12 highly-trained cyclists (mean ± SD: age; 35 ± 8 y, mass; 74.5
Plews, Daniel   +3 more
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Underground Railroad bicycle route : [United States] / Adventure Cycling Association ; production manager, Carla Majernik ; cartography, ACA Routes and Maping Staff ; text, Michael McCoy

open access: yes, 2013
Revision June 2013-Aug. 2014.Other title Mobile, AL to Fulton, MS, 400.5 miles. Fulton, MS to Owensboro, KY, 435 miles. Owensboro, KY to Milford, OH, 373.5 miles. Milford, OH to Erie, PA, 418.5 miles. Erie, PA to Owen Sound, ON, 378 miles.
Adventure Cycling Association, cartographer;
core  

A matter of utility? Rationalising cycling, cycling rationalities

open access: yes, 2015
This paper discusses how dominant policy paradigms promote a ‘utility’ model of transport, prioritising the destruction of distance and the minimisation of time spent travelling.
Aldred, R.
core   +1 more source

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