Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Regenerating spent LiFePO<sub>4</sub> with tailored molecular groups: from bulk lattice repair to surface conductive coating for enhanced cycling stability. [PDF]
Chen Y +5 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Enhancing Cycling Stability of Aqueous Aluminum-Metal Batteries via LaCl<sub>3</sub>-Modulated Interfacial Reactions. [PDF]
Gao Y +12 more
europepmc +1 more source
Ultra-High Cycling Stability of 3D Flower-like Ce(COOH)3 for Supercapacitor Electrode via a Facile and Scalable Strategy. [PDF]
He Q +6 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Evaluation of the Interphase-Related Cycling Stability of Thin-Film Amino- and Hydroxy-Substituted Anthraquinone Electrodes for Sodium-Ion Batteries. [PDF]
Greussing V +8 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
MOF Derivatives Confined Within Self-Supporting Bamboo Substrates with Hierarchical Porous Architectures for Long-Term Cycling Stability in Zinc-Air Batteries. [PDF]
Guo Y +7 more
europepmc +1 more source
TiO2-LiF composite coating for improving NCM622 cathode cycling stability: one-step construction. [PDF]
Huang K +9 more
europepmc +1 more source

