Results 151 to 160 of about 132,098 (265)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Regenerating spent LiFePO₄ with tailored molecular groups: from bulk lattice repair to surface conductive coating for enhanced cycling stability. [PDF]

Chem Sci
Chen Y, Chen X, Zeng Z, Sun W, Yang Y, Ge P.   +5 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Enhancing Cycling Stability of Aqueous Aluminum-Metal Batteries via LaCl₃-Modulated Interfacial Reactions. [PDF]

Adv Sci (Weinh)
Gao Y, Załęski K, Coy E, Scheibe B, Szymański K, Yang Q, Mijowska E, Liu X, Jia R, Moszyński D, Hu L, Holze R, Chen X.   +12 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Evaluation of the Interphase-Related Cycling Stability of Thin-Film Amino- and Hydroxy-Substituted Anthraquinone Electrodes for Sodium-Ion Batteries. [PDF]

ACS Appl Energy Mater
Greussing V, Werner D, Wielend D, Irimia CV, Leeb E, Ciganek M, Krajčovič J, Irimia-Vladu M, Portenkirchner E.   +8 more
europepmc   +1 more source

TiO₂-LiF composite coating for improving NCM622 cathode cycling stability: one-step construction. [PDF]

RSC Adv, 2023
Huang K, Zhou J, Yang H, Xie T, Lan T, Ong S, Jiang H, Zeng Y, Guo H, Zhang Y.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

MOF Derivatives Confined Within Self-Supporting Bamboo Substrates with Hierarchical Porous Architectures for Long-Term Cycling Stability in Zinc-Air Batteries. [PDF]

Materials (Basel)
Guo Y, Feng A, Peng Y, Liu X, Lin S, Liu P, Zu Y, Li X.   +7 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source