Results 71 to 80 of about 216,387 (290)
Exploring endoperoxides as a new entry for the synthesis of branched azasugars
Beilstein Journal of Organic Chemistry, 2017 A new class of nitrogen-containing endoperoxides were synthesised by a photochemical [4 + 2]-cycloaddition between a diene and singlet oxygen. The endoperoxides were dihydroxylated and protected to provide a series of endoperoxide building blocks for ...
Svenja Domeyer +3 more
doaj +1 more source
Addition and cycloaddition reactions of allenyl cations with various cycloalka-1,3-dienes [PDF]
, 1981 Allenyl cations , generated from propargyl chlorides and zinc chloride give monocyclic adducts or [3+4] and [2+4] cycloaddition products with various cycloalka-1,3-dienes.
Mayr, Herbert, Schütz, Franz
core +1 more source
Application of chiral 2-isoxazoline for the synthesis of syn-1,3-diol analogs
Beilstein Journal of Organic Chemistry, 2019 The asymmetric cycloaddition of TIPS nitronate catalyzed by “Cu(II)-bisoxazoline” gave the 2-isoxazoline product in 95% yield, which was converted into tert-butyl (3S,5R)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate in 14 steps through a β ...
Juanjuan Feng +3 more
doaj +1 more source
Synthesis of Bicyclic Isoxazoles and Isoxazolines via Intramolecular Nitrile Oxide Cycloaddition
Molecules, 2015 An efficient and straight forward procedure for the syntheses of bicyclic isoxazole/isoxazoline derivatives from the corresponding dimethyl-2-(2-nitro-1-aryl/alkyl)-2-(prop-2-yn-1yl)malonates or dimethyl 2-allyl-2-(2-nitro-1-aryl/alkyl ethyl)malonate is ...
Wen-Chang Chen +8 more
doaj +1 more source
Potential of cycloaddition reactions to generate cytotoxic metal drugs in vitro [PDF]
, 2014 Severe general toxicity issues blight many chemotherapeutics utilized in the treatment of cancers, resulting in the need for more selective drugs able to exert their biological activity at only the required location(s).
Crot, Stéphanie +3 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2014 The regioselective three-component condensation of azomethine ylides derived from isatins and α-amino acids with acrylamides or aroylacrylic acids as dipolarophiles has been realized through a one-pot 1,3-dipolar cycloaddition protocol.
Tatyana L. Pavlovskaya +6 more
doaj +1 more source
Synthetic Studies on Erythromycin Derivatives: Reactivity of the C12-21 Alkene
Molecules, 2006 The reactivity of the C12-21 alkene of some erythromycin A derivatives was studied. This double bond was easily oxidized to the corresponding epoxide with excellent stereoselectivity. A single crystal X-ray structure showed that the epoxide moiety was on
Wei-Min Chen
doaj +1 more source
Molecules, 2023 The involvement of 1,3-dipolar cycloaddition (1,3-DP), double bond migration, metathesis, and nitrile oxide (including in situ-generated nitrile oxide) as dipoles, together with the C=C bond containing dipolarophiles, in the syntheses of 2-isoxazolines ...
Stanisław Krompiec +7 more
doaj +1 more source
A Stepwise [4 + 3] Cycloaddition Reaction of the 1,3-Diphenyl-2-azaallyl Anion [PDF]
, 1993 The 1,3-diphenyl-2-azaallyl anion (1) undergoes [3 + 2] cycloaddition reactions with the s-cis-fixed 1,3-dienes 8-11. In contrast, 1,1,2,2,3,3-hexamethyl-4,5-bis(methylene)cyclopentane (7) reacts with 1 to give the [4 + 3] cycloadduct 13 and the linear 1,
Anh +23 more
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Bioconjugate chemistry, 2017 Interrogating biological systems is often limited by access to biological probes. The emergence of "click chemistry" has revolutionized bioconjugate chemistry by providing facile reaction conditions amenable to both biologic molecules and small molecule ...
Chad J. Pickens +4 more
semanticscholar +1 more source