Results 71 to 80 of about 27,486 (241)
Angewandte Chemie, EarlyView.A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho +9 more
wiley +2 more sources
Cycloadditions as a Sweet Route to ‘Double C-Glycosylation’
BiomoleculesPharmaceuticals, such as the antibiotic erythromycin, and sodium-dependent glucose transporter (SGLT1 & SGTL2) inhibitors such as Bexagliflozin (diabetes) and Sotagliflozin (heart disease), are often sugar-decorated (glycosylated). Glycosylation is a key
Kevin P. P. Mahoney +8 more
doaj +1 more source
Synthesis of aryl-1H-1,2,3-triazoles via 1,3-dipolar cycloaddition
Orbital: The Electronic Journal of Chemistry, 2012 A series of Aryl-1H-1,2,3-triazoles were prepared from the reaction between aril-azide (1) with 1.5 equiv. of terminal alkynes (2a-o). The reactions carried out at room temperature and in the presence of CuI (10 mol%) in acetonitrile. The compounds (3a-o)
Wagner O. Valença +2 more
doaj +1 more source
Palladium‐Catalyzed Annulations of an Anti‐Bredt Olefin
Angewandte Chemie, EarlyView.We report metal‐catalyzed trappings of a [2.2.1]‐bridged bicyclic anti‐Bredt olefin (ABO). The methodology yields unusual heterocyclic products and is expected to prompt the further development of unconventional reactions, including metal‐catalyzed processes of ABOs and other strained olefins. ABSTRACT A famous class of alkene‐containing compounds that
Zach G. Walters +3 more
wiley +2 more sources
International Journal of TechnologyThe capture, storage, and conversion of anthropogenic carbon dioxide (CO2) is one of the urgent environmental challenges. Among the various methods available, direct conversion is the most preferable.
Maria Atlaskina +9 more
doaj +1 more source
Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition
Angewandte Chemie, EarlyView.A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando +10 more
wiley +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2019 The common feature of the four iridium(III) salt complexes, (bis{[(diphenylphosphanyl)methyl]diphenylphosphanylidene}(ethoxyoxoethanylidene)methane-κ4P,C,C′,P′)chloridohydridoiridium(III) chloride methylene chloride 2.75-solvate (4), (bis ...
Inge Schlapp-Hackl +6 more
doaj +1 more source
Mechanically Interlocked Indigo Photoswitches
Angewandte Chemie, EarlyView.By incorporating indigo photoswitches into the axle of a rotaxane, which features a hydrogen bonding macrocycle, we demonstrate improvement in activation wavelength, photostationary states and thermal reversion, an effect that is governed by topologically constrained supramolecular interactions.
Alexander M. Wilmshurst +9 more
wiley +2 more sources
Enantioselective cycloaddition reactions
ChemInform, 1991 Publisher Summary This chapter reviews the cycloadditions reactions because they are popular, widely used, and also constitutes enormous body of chemistry. The chapter focuses on the landmark achievements as well as state-of-the-art examples of relevant chemistry.
openaire +2 more sources
Angewandte Chemie, EarlyView.Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez +5 more
wiley +2 more sources