Results 161 to 170 of about 73,410 (278)

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

open access: yesChemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke   +5 more
wiley   +1 more source

Slow Release of Bioactive Alcohols From Butenolide Polymers and Coatings

open access: yesChemistry – A European Journal, EarlyView.
In this study we have reported the acid‐mediated release of bioactive alcohols from biobased alkoxy butenolide derived copolymers and coatings. It can potentially be applied for slow release of odors, pesticides, or drug‐related compounds from biobased polybutenolides.
Andries Jensma   +9 more
wiley   +1 more source

A DFT Study on the Mechanism of Selective Formation of Substituted Azepines From 1‐Azabutadienes and Cyclopropanes

open access: yesChemistry – A European Journal, EarlyView.
The origin of the unusual regioselectivity in the Mg‐catalyzed cyclization of azadiene‐type imines with cyclopropanes is elucidated by DFT calculations. Although five‐membered rings are typically favored, energy decomposition analysis reveals that severe steric congestion induces a highly distorted transition state, rendering the five‐membered pathway ...
Ryo Kobayashi   +5 more
wiley   +1 more source

Modeling cycloaddition reactions

open access: yes, 2020
Bu çalışmada, Diels-Alder ve 1,3-dipolar siklokatılmaları olmak üzere iki tip siklokatılma tepkimesinde seçicilikler incelendi.Birinci kısımda, farklı kiral dien ve akiral dienofiller kullanılarak hidrojen bağı destekli Diels-Alder reaksiyonlarındaki seçicilik Yoğunluk Fonksiyonları Teorisi (DFT) ile incelenmiştir.
openaire   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

open access: yesChemistry – A European Journal, EarlyView.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

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