Results 181 to 190 of about 2,202,700 (266)

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Author Correction: Evaluation of antibiofilm properties of dehydroacetic acid (DHA) grafted spiro-oxindolopyrrolidines synthesized via multicomponent 1,3-dipolar cycloaddition reaction. [PDF]

Sci Rep
Suresh Babu AR, Sharma A, Athira MP, Alajangi HK, Raj ARN, Gartia J, Singh G, Barnwal RP.   +7 more
europepmc   +1 more source

Study on Selected Metal-Organic Framework-Based Catalysts for Cycloaddition Reaction of CO₂ with Epoxides: A Highly Economic Solution for Carbon Capture and Utilization. [PDF]

Polymers (Basel), 2021
Musa SG, Aljunid Merican ZM, Akbarzadeh O.   +2 more
europepmc   +1 more source

Mechanistic Basis of the Cu(OAc)₂ Catalyzed Azide-Ynamine (3 + 2) Cycloaddition Reaction. [PDF]

J Am Chem Soc
Bunschoten RP, Peschke F, Taladriz-Sender A, Alexander E, Andrews MJ, Kennedy AR, Fazakerley NJ, Lloyd Jones GC, Watson AJB, Burley GA.   +9 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Efficient synthesis of tetrazoles <i>via</i> [2 + 3] cycloaddition reaction catalyzed by cobalt-nickel on magnetic mesoporous hollow spheres. [PDF]

RSC Adv
Ansari M, Ghasemi AH, Naeimi H.
europepmc   +1 more source

Investigations into a Stoichiometrically Equivalent Intermolecular Oxidopyrylium [5 + 2] Cycloaddition Reaction Leveraging 3-Hydroxy-4-pyrone-Based Oxidopyrylium Dimers. [PDF]

J Org Chem, 2021
Schiavone DV, Kapkayeva DM, Murelli RP.
europepmc   +1 more source

Utilizing MEDT analysis of [3 + 2] cycloaddition reaction: x-ray crystallography of spirooxindole linked with thiophene/furan heterocycles and triazole framework. [PDF]

BMC Chem
Alayyaf AA, Ali M, Alwehaibi MA, Al-Muhanna MK, Soliman SM, Ríos-Gutiérrez M, Haukka M, Barakat A.   +7 more
europepmc   +1 more source

Synthesis of a Stable Hydrophilic trans‐Cyclooctene Amino Acid Unlocks Fast Bioorthogonal Click Chemistry for the Generation of Antibody‐Drug Conjugates by Genetic Code Expansion

Angewandte Chemie International Edition, EarlyView.
A novel trans‐cyclooctene (TCO) based noncanonical amino acid (ncAA) is reported, characterized by high hydrophilicity and remarkable stability to trans‐cis isomerization. Its incorporation via genetic code expansion into an antibody and subsequent conjugation resulted in a highly efficacious antibody‐drug conjugate (ADC).
Georgi R. Genov, Dina Osmanović, Ines Bašić, Christine Koehler, Paul F. Sauter   +4 more
wiley   +1 more source

Theoretical Study of the Mechanism of the Formation of Azomethine Ylide from Isatine and Sarcosine and Its Reactivity in 1,3-Dipolar Cycloaddition Reaction with 7-Oxabenzonorbornadiene. [PDF]

Int J Mol Sci
Antol I, Štrbac P, Murata Y, Margetić D.   +3 more
europepmc   +1 more source