Results 81 to 90 of about 72,904 (250)
Angewandte Chemie, EarlyView.Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and tryptophan residues via the Mannich reaction. These cyclic imine warheads show comparable reaction kinetics to cysteine‐reactive electrophiles commonly used in TCIs.
Sijie Wang +6 more
wiley +2 more sources
[2+2]-cycloadditions of alkenes with the triphenylallenyl cation [PDF]
, 1984 The triphenylallenyl cation (8), generated from triphenylpropynol (7) and FSO3H, reacts with alkenes to give the allyl cations 12, which may be deprotonated to yield the methyleneccylobutenes 14.
Deno +13 more
core +1 more source
Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials
Advanced Science, EarlyView.Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon +3 more
wiley +1 more source
Hydrophilic Janus Micelles From an ABC Triblock Copolymer
Angewandte Chemie, EarlyView.An amphiphilic triblock copolymer with poly(ethylene glycol) (PEG) and poly(N‐vinylpyrrolidone) (PVP) coronas self‐assembles into spherical micelles with Janus‐type surface segregation in water. Cryo‐TEM, enabled by selective PVP labeling, and 1H‐NOESY NMR reveal phase separation.
José Muñoz‐López +5 more
wiley +2 more sources
Cycloaddition Reactions of Heterophospholes
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Raj K. Bansal +2 more
openaire +1 more source
Development of a Novel Epoxide-Containing Trimethylenemethane Precursor for Palladium-Catalyzed Cycloadditions [PDF]
, 2019 Pd(0)-catalyzed trimethylenemethane (TMM) cycloaddition reactions have been used extensively to generate disubstituted 5-membered rings with high levels of regioselectivity, chemoselectivity, and stereoselectivity.
Paterson, Mara
core +2 more sources
Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]
, 2019 Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu +6 more
core +1 more source
Advanced Science, EarlyView.A cascade recognition of activatable probe ANG‐hCy‐MC is used for high‐precision depiction of glioblastoma (GBM) margin. This probe crosses the blood‐brain barrier (BBB) through LRP1 receptor‐mediated transport and provides excellent fluorescence signal contrast between the tumor and normal tissues, thereby enabling ultra‐selective imaging and precise ...
Xinru An +8 more
wiley +1 more source
An ab initio study of the mechanism of the cycloaddition reaction forming bicyclic compounds between vinylidene (H2C=C:) and ethylene [PDF]
Journal of the Serbian Chemical Society, 2011 The mechanism of the cycloaddition reaction forming a bicyclic compounds between singlet vinylidene (H2C=C:) and ethylene was investigated using the CCSD(T)//MP2/6-31G* method. From the potential energy profile, it can be predicted that this reaction has
YONGQING LI, ZHENXIA LIAN, XIUHUI LU
doaj
Advanced Science, EarlyView.We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley +1 more source