Results 91 to 100 of about 14,856 (220)

Ligand-controlled regiodivergent aminocarbonylation of cyclobutanols toward 1,1- and 1,2-substituted cyclobutanecarboxamides

Nature Communications
Four-membered carbocycles are among the most sought-after backbones which are commonly found in biologically active molecules. However, difficulties on their producing are existing due to its highly strained ring system.
Xing-Wei Gu, Yan-Hua Zhao, Xiao-Feng Wu
doaj   +1 more source

Synthesis of Cis-Diammine (1,1-cyclobutane dicarboxylate) Platinum(II) [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
Platinum-based anticancer drugs are chemotherapeutic agents to treat cancer. Carboplatin (cis diammine cyclobutane dicarboxylate platinum (II)) is a second generation drug that has less toxic than cisplatin, allowing for high dosages. In the first stage,
Ali Nemati kharat, Bahareh Tamaddoni Jahromi, Ehsan Mohammadifar, Jaleh Zareyi   +3 more
doaj  

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez, Henry W. Lim, Salvador González   +5 more
wiley   +1 more source

Skeleton-rearranged pentacyclic diterpenoids possessing a cyclobutane ring from Euphorbia wallichii

, 2006
Two novel rearranged trachylobane diterpenoids, designated as wallichanol A (2) and wallichanol B (3), consisting of an unprecedented pentacyclic skeleton named wallichane with a cyclobutane ring, and a new ent-trachylobane diterpenoid, 3-oxo-ent ...
Zhou, P, Peng, SL, Zhang, XF, Ding, LS, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China., Pan, L, Ding, LS, Qiu, SX   +6 more
core  

Twist and turn: a revised structural view on the unpaired bubble of class II CPD photolyase in complex with damaged DNA

IUCrJ, 2018
Cyclobutane pyrimidine dimer (CPD) photolyases harness the energy of blue light to repair UV-induced DNA CPDs. Upon binding, CPD photolyases cause the photodamage to flip out of the duplex DNA and into the catalytic site of the enzyme.
Manuel Maestre-Reyna, Junpei Yamamoto, Wei-Cheng Huang, Ming-Daw Tsai, Lars-Oliver Essen, Yoshitaka Bessho   +5 more
doaj   +1 more source

The Thermal Decomposition of Cyclobutane [PDF]

Proceedings of the National Academy of Sciences, 1952
F, Kern, W D, Walters
openaire   +2 more sources

Photochemisch erzeugte Oxetane als Schlüssel zur endergonen Cyclopropansynthese

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
Eine neuartige Oxetan‐zu‐Cyclopropan‐Umlagerung eröffnet einen atomökonomischen Zugang zu dicht funktionalisierten Cyclopropanen aus Furanen und photochemisch aktivierten Aldehyden. Die erhaltenen Strukturen erschließen komplexe bioaktive Motive und fungieren als vielseitige Plattform für die asymmetrische Cyclopropansynthese.
Tim Köglmeier, Thomas J. Tiefel, Oliver Reiser   +2 more
wiley   +1 more source

Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation

Angewandte Chemie International Edition, Volume 65, Issue 35, 24 August 2026.
An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier, Thomas J. Tiefel, Oliver Reiser   +2 more
wiley   +1 more source

Enantioselective synthesis of a cyclobutane analogue of Milnacipran

, 2017
An optically active cyclobutane analogue of Milnacipran was synthesized from phenylacetonitrile, and its cis-stereochemistry was controlled by an epimerization step.
Dinh-Vu Nguyen, David-Alexandre Buisson, Marc Nicolas, Edmond Gravel, Eric Doris   +4 more
core   +1 more source

Structural basis of cyclobutane pyrimidine dimer recognition by UV-DDB in the nucleosome

Nature Communications
In mammalian global genomic nucleotide excision repair, UV-DDB plays a central role in recognizing DNA lesions, such as 6-4 photoproducts and cyclobutane pyrimidine dimers, within chromatin.
Syota Matsumoto, Yoshimasa Takizawa, Mitsuo Ogasawara, Kana Hashimoto, Lumi Negishi, Wenjie Xu, Haruna Tachibana, Junpei Yamamoto, Shigenori Iwai, Kaoru Sugasawa, Hitoshi Kurumizaka   +10 more
doaj   +1 more source