Results 91 to 100 of about 23,086 (229)
The stereochemistry of the title compound, C32H44O10, at the cyclobutane ring is cis-anti-cis. The molecule lies across an inversion center. In the crystal, weak C—H...O hydrogen bonds connect molecules into chains along [100], forming R22(6 ...
Alan J. Lough, Kelsey Jack, William Tam
doaj +1 more source
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
doaj +1 more source
UV-Induced Structural Changes of Model DNA Helices Probed by Optical Spectroscopy [PDF]
International audienceChemical alterations of DNA, if not repaired, may lead to carcinogenic mutations. Structural modifications of the helix around the lesion enable its recognition by repair enzymes.
Bányász, A. +4 more
core +4 more sources
Dibenzazepin‐verbrückte Netzwerk‐Polymer‐Phthalocyanine als abbaubare heterogene Photokatalysatoren
Photodynamische Dibenzazepin‐Brücke wurde in Zink‐ und Kobalt‐Netzwerk‐Polymer‐Phthalocyanine (NP‐Pcs) eingeführt, um abbaubare heterogene Photokatalysatoren zu erhalten. Zum ersten Mal spielt die Bestrahlung mit Licht eine Schlüsselrolle beim „Design, der Verwendung und dem Abbau” von NP‐Pcs.
Erem Ahmetali +4 more
wiley +1 more source
Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Hiroyuki Niida +14 more
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Dibenzazepine Bridged Network Polymeric Phthalocyanines as Degradable Heterogeneous Photocatalysts
Dibenzazepine photodynamic bridge has been introduced to zinc and cobalt networks phthalocyanines (NP‐Pcs) to obtain degradable heterogeneous photocatalysts. For the first time, light irradiation plays a key role in “design, use and degradation” of NP‐Pcs.
Erem Ahmetali +4 more
wiley +1 more source
Synthesis of Cis-Diammine (1,1-cyclobutane dicarboxylate) Platinum(II) [PDF]
Platinum-based anticancer drugs are chemotherapeutic agents to treat cancer. Carboplatin (cis diammine cyclobutane dicarboxylate platinum (II)) is a second generation drug that has less toxic than cisplatin, allowing for high dosages. In the first stage,
Ali Nemati kharat +3 more
doaj
Four-membered carbocycles are among the most sought-after backbones which are commonly found in biologically active molecules. However, difficulties on their producing are existing due to its highly strained ring system.
Xing-Wei Gu, Yan-Hua Zhao, Xiao-Feng Wu
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Cyclobutane pyrimidine dimer (CPD) photolyases harness the energy of blue light to repair UV-induced DNA CPDs. Upon binding, CPD photolyases cause the photodamage to flip out of the duplex DNA and into the catalytic site of the enzyme.
Manuel Maestre-Reyna +5 more
doaj +1 more source
Structural basis of cyclobutane pyrimidine dimer recognition by UV-DDB in the nucleosome
In mammalian global genomic nucleotide excision repair, UV-DDB plays a central role in recognizing DNA lesions, such as 6-4 photoproducts and cyclobutane pyrimidine dimers, within chromatin.
Syota Matsumoto +10 more
doaj +1 more source

