Results 1 to 10 of about 92 (85)

Supramolecular construction of a cyclobutane ring system with four different substituents in the solid state

open access: yesCommunications Chemistry, 2021
Preparation of cyclobutanes with four different substituents is rare and often arduous. Here a cocrystallisation strategy enables the intermolecular [2+2] cross-photoreaction of non-symmetrical stilbene derivatives to obtain chiral tetrasubstituted ...
Michael A. Sinnwell   +4 more
doaj   +1 more source

Methodology-driven efficient synthesis of cytotoxic (±)-piperarborenine B

open access: yesGreen Synthesis and Catalysis, 2022
The evolution of synthetic design toward the efficient synthesis of cyclobutane natural product (±)-piperarborenine B is demonstrated. Taking the advantages of good functional group compatibility of contractive synthesis of cyclobutanes from pyrrolidines,
Chunngai Hui, Andrey P. Antonchick
doaj   +1 more source

The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes

open access: yesЖурнал органічної та фармацевтичної хімії, 2023
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova   +2 more
doaj   +1 more source

Skeletal contraction: A novel strategy to access multisubstituted cyclobutane

open access: yesGreen Synthesis and Catalysis, 2022
The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.
Chunfa Xu   +2 more
doaj   +1 more source

Radical cation Diels–Alder reactions of arylidene cycloalkanes

open access: yesBeilstein Journal of Organic Chemistry, 2022
TiO2 photoelectrochemical and electrochemical radical cation Diels–Alder reactions of arylidene cycloalkanes are described, leading to the construction of spiro ring systems.
Kaii Nakayama   +2 more
doaj   +1 more source

Cage-confined photocatalysis for wide-scope unusually selective [2 + 2] cycloaddition through visible-light triplet sensitization

open access: yesNature Communications, 2020
Light-induced [2 + 2] cycloaddition is the most efficient way to generate cyclobutanes, while suffering from limitations of specific selectivity.
Jing-Si Wang   +8 more
doaj   +1 more source

Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives

open access: yesMolecules, 2019
The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms.
Noha Hasaneen   +8 more
doaj   +1 more source

Contemporary synthesis of bioactive cyclobutane natural products

open access: yesGreen Synthesis and Catalysis, 2023
Many cyclobutane natural products have intriguing biological properties that arise from their fascinating chemical structures. Cyclobutane natural products feature a cyclobutane scaffold as the core or as a part of the spirocyclic or fused cyclic core ...
Chunngai Hui   +3 more
doaj   +1 more source

Stereoselective Synthesis of Bicyclo[3.1.1]Heptane Derivatives via Intramolecular Photocycloaddition Reaction

open access: yesNatural Product Communications, 2012
Optically active 1,3-bridged cyclobutanes 10 of the bicyclo[3.1.1]heptane ring system and 1,2-bridged cyclobutanes 11 of the bicyclo[3.2.0]heptane ring system were produced by UV irradiation of α,β,γ,δ-unsaturated esters 9a and 9c-f.
Kiyoshi Honda   +6 more
doaj   +1 more source

9a-Phenyl-2,3,3a,3b,9a,9b-hexahydro-4H-furo[3‘,2’:3,4]cyclobuta- [1,2-b]chromen-4-one: A Flavone-Based [2 + 2]-Photocycloadduct

open access: yesMolbank, 2021
The intermolecular [2 + 2]-photocycloaddition of the parent flavone molecule (4) as the triplet energy-accepting species and the electron-rich alkene 2, 3-dihydrofuran (5) was performed by visible-light-mediated triplet-sensitization with an iridium ...
Jens Lefarth   +2 more
doaj   +1 more source

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