Results 1 to 10 of about 92 (85)
Preparation of cyclobutanes with four different substituents is rare and often arduous. Here a cocrystallisation strategy enables the intermolecular [2+2] cross-photoreaction of non-symmetrical stilbene derivatives to obtain chiral tetrasubstituted ...
Michael A. Sinnwell +4 more
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Methodology-driven efficient synthesis of cytotoxic (±)-piperarborenine B
The evolution of synthetic design toward the efficient synthesis of cyclobutane natural product (±)-piperarborenine B is demonstrated. Taking the advantages of good functional group compatibility of contractive synthesis of cyclobutanes from pyrrolidines,
Chunngai Hui, Andrey P. Antonchick
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The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova +2 more
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Skeletal contraction: A novel strategy to access multisubstituted cyclobutane
The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.
Chunfa Xu +2 more
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Radical cation Diels–Alder reactions of arylidene cycloalkanes
TiO2 photoelectrochemical and electrochemical radical cation Diels–Alder reactions of arylidene cycloalkanes are described, leading to the construction of spiro ring systems.
Kaii Nakayama +2 more
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Light-induced [2 + 2] cycloaddition is the most efficient way to generate cyclobutanes, while suffering from limitations of specific selectivity.
Jing-Si Wang +8 more
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The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms.
Noha Hasaneen +8 more
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Contemporary synthesis of bioactive cyclobutane natural products
Many cyclobutane natural products have intriguing biological properties that arise from their fascinating chemical structures. Cyclobutane natural products feature a cyclobutane scaffold as the core or as a part of the spirocyclic or fused cyclic core ...
Chunngai Hui +3 more
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Optically active 1,3-bridged cyclobutanes 10 of the bicyclo[3.1.1]heptane ring system and 1,2-bridged cyclobutanes 11 of the bicyclo[3.2.0]heptane ring system were produced by UV irradiation of α,β,γ,δ-unsaturated esters 9a and 9c-f.
Kiyoshi Honda +6 more
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The intermolecular [2 + 2]-photocycloaddition of the parent flavone molecule (4) as the triplet energy-accepting species and the electron-rich alkene 2, 3-dihydrofuran (5) was performed by visible-light-mediated triplet-sensitization with an iridium ...
Jens Lefarth +2 more
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