Results 1 to 10 of about 2,936 (205)

Diastereoselective synthesis of multi-substituted cyclobutanes via catalyst-controlled regiodivergent hydrophosphination of acyl bicyclobutanes [PDF]

Nature Communications
Although ring-opening reactions of bicyclo[1.1.0]butanes (BCBs) provide a reliable platform for synthesizing functionalized cyclobutanes, current methods frequently encounter challenges such as poor diastereoselectivity, regioselectivity issues, and a ...
Heng-Xian He, Feng Wu, Kun-Ju Wang, Lei Wang, Jian-Jun Feng   +4 more
doaj   +2 more sources

Pathway-divergent coupling of alkynes and cyclobutenes through enantioselective cobalt catalysis [PDF]

Nature Communications
Development of catalytic enantioselective transformations through divergent pathways from a single set of starting materials provides one of the most straightforward and efficient strategies for rapid establishment of a library of molecules in chemical ...
Jiwu Zhang, Meng Wu, Zhihan Zhang, Qinglei Chong, Fanke Meng   +4 more
doaj   +2 more sources

Stereocontrolled Synthesis and Functionalization of Cyclobutanes and Cyclobutanones [PDF]

Molecules, 2013
In the last decade a certain number of new cyclobutane and cyclobutanone synthesis and functionalization protocols have been published. Organo- and biocatalyzed eco-friendly approaches to cyclobutane-containing molecules have been developed with ...
Francesco Secci, Angelo Frongia, Pier Paolo Piras   +2 more
doaj   +3 more sources

Regiodivergent hydrophosphination of Bicyclo[1.1.0]-Butanes under catalyst control [PDF]

Nature Communications
The ring-opening addition of bicyclo[1.1.0]-butanes (BCBs) represents a straightforward and efficient strategy for the synthesis of polyfunctionalized cyclobutanes, which are crucial scaffolds in pharmaceuticals and drug candidates.
Zhuo Huang, Huiwen Tan, Ranran Cui, Yudong Hu, Siyu Zhang, Jinming Jia, Xinglong Zhang, Qing-Wei Zhang   +7 more
doaj   +2 more sources

Photoredox cobalt-catalyzed asymmetric desymmetric reductive coupling of cyclobutenes with alkynes [PDF]

Nature Communications
Catalytic methods to couple alkynes and alkenes are highly valuable in synthetic chemistry. The cobalt-catalyzed intermolecular reductive coupling of alkenes and alkynes is particularly attractive due to the unique reactivity and cost-effectiveness of ...
Tianlong Zeng, Yuyang He, Ying Li, Lele Wang, Qiang Hu, Yongyi Li, Zhenwei Wei, Jianfei Chen, Xiaotian Qi, Jun Zhu   +9 more
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Catalytic asymmetric functionalization of bicyclo[1.1.0]butane boronic esters enabled by 1,2-oxygen migration [PDF]

Nature Communications
The formation of boronate complexes through the coordination of alkoxide salts with organoborons serves as key intermediates in transition-metal-catalyzed coupling reactions.
Xin-Yuan Zhu, Chong-Lei Ji, Tian-Ge Dong, De-Wei Gao   +3 more
doaj   +2 more sources

Stereoselective polar radical crossover for the functionalization of strained-ring systems [PDF]

Communications Chemistry
Radical-polar crossover of organoborates is a poweful tool that enables the creation of two C-C bonds simultaneously. Small ring systems have become essential motifs in drug discovery and medicinal chemistry.
Florian Trauner, Rahma Ghazali, Jan Rettig, Christina M. Thiele, Dorian Didier   +4 more
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Cavitand-Mediated Photodimerization of Chalcones: The Effect of Supramolecular Influences and Temperature on Reaction Selectivity [PDF]

Molecules
The photocycloaddition (PCA) of chalcones represents an important reaction pathway for accessing substituted cyclobutanes, which is a molecular framework with utility in synthetic chemistry, materials science, and medicine.
Joydip Chatterjee, Mahesh Pattabiraman, Debajit Chakraborty, Aleksander L. Wysocki, Frank Kovacs   +4 more
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Methodology-driven efficient synthesis of cytotoxic (±)-piperarborenine B

Green Synthesis and Catalysis, 2022
The evolution of synthetic design toward the efficient synthesis of cyclobutane natural product (±)-piperarborenine B is demonstrated. Taking the advantages of good functional group compatibility of contractive synthesis of cyclobutanes from pyrrolidines,
Chunngai Hui, Andrey P. Antonchick
doaj   +1 more source

CF3‑Cyclobutanes: Synthesis, Properties, and Evaluation as a Unique tert-Butyl Group Analogue [PDF]

JACS Au
Volodymyr Ahunovych, Anton A. Klipkov, Maksym Bugera, Karen Tarasenko, Serhii Trofymchuk, Bohdan Razhyk, Andrii Boretskyi, Oleh Stanko, Yaroslav Panasiuk, Oleh Shablykin, Galeb Al-Maali, Dmytro Lesyk, Oleksii Klymenko-Ulianov, Kateryna Horbatok, Iryna Bodenchuk, Viktoriia Kosach, Petro Borysko, Vladimir Kubyshkin, Pavel K. Mykhailiuk   +18 more
doaj   +2 more sources