Results 1 to 10 of about 400 (141)
Contemporary synthesis of bioactive cyclobutane natural products
Many cyclobutane natural products have intriguing biological properties that arise from their fascinating chemical structures. Cyclobutane natural products feature a cyclobutane scaffold as the core or as a part of the spirocyclic or fused cyclic core ...
Yusheng Xie, Junyang Liu
exaly +3 more sources
Stereocontrolled Synthesis and Functionalization of Cyclobutanes and Cyclobutanones [PDF]
In the last decade a certain number of new cyclobutane and cyclobutanone synthesis and functionalization protocols have been published. Organo- and biocatalyzed eco-friendly approaches to cyclobutane-containing molecules have been developed with ...
Francesco Secci +2 more
doaj +3 more sources
Synthesis of cyclobutane analogues
2-(3-Acetyl-2,2-dimethylcyclobutyl)acetic acid (pinonic acid) was synthesized using α-pinene as raw material and potassium permanganate as oxidant. This compound reacted with substituted aniline to produce eight kinds of derivatives with cyclobutane ...
Yan Bai Yin +4 more
doaj +2 more sources
Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids
This review focuses on the rare group of carbon-bridged steroids (CBS) and triterpenoids found in various natural sources such as green, yellow-green, and red algae, marine sponges, soft corals, ascidians, starfish, and other marine invertebrates.
Valery M. Dembitsky +2 more
doaj +1 more source
The formation and crystal structure of a zigzag network held together by I...N halogen bonds is reported. In particular, the halogen-bond donor is 1,3-diiodoperchlorobenzene (C6I2Cl4) while the acceptor is the photoproduct rtct-tetrakis(pyridin-4-yl ...
Eric Bosch +3 more
doaj +1 more source
The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova +2 more
doaj +1 more source
Aim. To synthesize cis- and trans-isomers of 3-(4-hydroxyphenyl)cyclobutanecarboxylic acid and evaluate the biological activity of their derivatives against GPR-40. Results and discussion.
I. O. Feskov +5 more
doaj +1 more source
The ditopic halogen-bond (X-bond) donors 1,2-, 1,3-, and 1,4-diiodotetrafluorobenzene (1,2-, 1,3-, and 1,4-di-I-tFb, respectively) form binary cocrystals with the unsymmetrical ditopic X-bond acceptor trans-1-(2-pyridyl)-2-(4-pyridyl)ethylene (2,4-bpe ...
Jay Quentin +2 more
doaj +1 more source
Aim. To synthesize cyclobutane-derived amines and carboxylic acids bearing CH2F or CHF2 groups in the α position; to determine the regularities of the effect of fluoroalkyl substituents on the acid-base properties of the title compounds.
Oleksandr Demchuk, Oleksandr Grygorenko
doaj +1 more source
The halogen-bond (X-bond) donors 1,3- and 1,4-diiodotetrafluorobenzene (1,3-di-I-tFb and 1,4-di-I-tFb, respectively) form cocrystals with trans-1,2-bis(2-pyridyl)ethylene (2,2′-bpe) assembled by N···I X-bonds.
Jay Quentin +2 more
doaj +1 more source

