Results 11 to 20 of about 2,936 (205)

Stereoselective synthesis of cyclobutanes by contraction of pyrrolidines [PDF]

, 2021
Here we report a contractive synthesis of multisubstituted cyclobutanes containing multiple stereocenters from readily accessible pyrrolidines using iodonitrene chemistry.
Brieger, L, Antonchick, AP, Strohmann, C, Brieger, L., Strohmann, C., Hui, C., Antonchick, A., Hui, C   +7 more
core   +2 more sources

Supramolecular construction of a cyclobutane ring system with four different substituents in the solid state

Communications Chemistry, 2021
Preparation of cyclobutanes with four different substituents is rare and often arduous. Here a cocrystallisation strategy enables the intermolecular [2+2] cross-photoreaction of non-symmetrical stilbene derivatives to obtain chiral tetrasubstituted ...
Michael A. Sinnwell, Ryan H. Groeneman, Benjamin J. Ingenthron, Changan Li, Leonard R. MacGillivray   +4 more
doaj   +1 more source

The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes

Журнал органічної та фармацевтичної хімії, 2023
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova, Alona S. Cherednichenko, Yuliya V. Rassukana   +2 more
doaj   +1 more source

Skeletal contraction: A novel strategy to access multisubstituted cyclobutane

Green Synthesis and Catalysis, 2022
The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.
Chunfa Xu, V.U. Bhaskara Rao, Fen-Er Chen   +2 more
doaj   +1 more source

Stereoretentive Formation of Cyclobutanes from Pyrrolidines: Lessons Learned from DFT Studies of the Reaction Mechanism

, 2023
The stereoselective synthesis of cyclobutanes that possess an array of stereocenters in a contiguous fashion has attracted the wide interest of the synthetic community.
Roger Monreal-Corona (14818063), Anna Pla-Quintana (1581502), Miquel Solà (1378155), Albert Poater (1377699)   +3 more
core   +2 more sources

Radical cation Diels–Alder reactions of arylidene cycloalkanes

Beilstein Journal of Organic Chemistry, 2022
TiO2 photoelectrochemical and electrochemical radical cation Diels–Alder reactions of arylidene cycloalkanes are described, leading to the construction of spiro ring systems.
Kaii Nakayama, Hidehiro Kamiya, Yohei Okada   +2 more
doaj   +1 more source

NMR and Computational Studies on the Reactions of Enamines with Nitroalkenes That May Pass through Cyclobutanes [PDF]

ACS Omega, 2019
The addition of aldehyde enamines to nitroalkenes affords cyclobutanes in all solvents, with all of the pyrrolidine and proline derivatives tested by us and with all of the substrates we have examined. Depending on the temperature, concentration of water,
Alejandro Castro-Alvarez, Héctor Carneros, Jaume Calafat, Anna M. Costa, Cristian Marco, Jaume Vilarrasa   +5 more
doaj   +3 more sources

Cage-confined photocatalysis for wide-scope unusually selective [2 + 2] cycloaddition through visible-light triplet sensitization

Nature Communications, 2020
Light-induced [2 + 2] cycloaddition is the most efficient way to generate cyclobutanes, while suffering from limitations of specific selectivity.
Jing-Si Wang, Kai Wu, Changzhen Yin, Kang Li, Yahao Huang, Jia Ruan, Ximin Feng, Peng Hu, Cheng-Yong Su   +8 more
doaj   +1 more source

Contemporary synthesis of bioactive cyclobutane natural products

Green Synthesis and Catalysis, 2023
Many cyclobutane natural products have intriguing biological properties that arise from their fascinating chemical structures. Cyclobutane natural products feature a cyclobutane scaffold as the core or as a part of the spirocyclic or fused cyclic core ...
Chunngai Hui, Zhuo Wang, Yusheng Xie, Junyang Liu   +3 more
doaj   +1 more source

PolyBorylated Alkenes as Energy-Transfer Reactive Groups for the Generation of polyBorylated Biradicals: Access to Multi-Borylated Cyclobutanes Combined with 1,5-HAT Event

, 2023
While polyborylated alkenes are being recognized for their elevated status as highly valuable reagents in modern organic synthesis, allowing efficient access to a diverse array of transformations, including the formation of C–C and C–heteroatom bonds ...
Nicole, Hanania, Nadim, Eghbarieh, Ahmad, Masarwa   +2 more
core   +1 more source