Results 11 to 20 of about 2,217 (174)

The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes

Журнал органічної та фармацевтичної хімії, 2023
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic
Anastasiia M. Aleksandrova, Alona S. Cherednichenko, Yuliya V. Rassukana   +2 more
doaj   +1 more source

Skeletal contraction: A novel strategy to access multisubstituted cyclobutane

Green Synthesis and Catalysis, 2022
The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.
Chunfa Xu, V.U. Bhaskara Rao, Fen-Er Chen   +2 more
doaj   +1 more source

CF₃-Cyclobutanes: Synthesis, Properties, and Evaluation as a Unique tert-Butyl Group Analogue. [PDF]

JACS Au
Ahunovych V, Klipkov AA, Bugera M, Tarasenko K, Trofymchuk S, Razhyk B, Boretskyi A, Stanko O, Panasiuk Y, Shablykin O, Al-Maali G, Lesyk D, Klymenko-Ulianov O, Horbatok K, Bodenchuk I, Kosach V, Borysko P, Kubyshkin V, Mykhailiuk PK.   +18 more
europepmc   +2 more sources

Radical cation Diels–Alder reactions of arylidene cycloalkanes

Beilstein Journal of Organic Chemistry, 2022
TiO2 photoelectrochemical and electrochemical radical cation Diels–Alder reactions of arylidene cycloalkanes are described, leading to the construction of spiro ring systems.
Kaii Nakayama, Hidehiro Kamiya, Yohei Okada   +2 more
doaj   +1 more source

Cage-confined photocatalysis for wide-scope unusually selective [2 + 2] cycloaddition through visible-light triplet sensitization

Nature Communications, 2020
Light-induced [2 + 2] cycloaddition is the most efficient way to generate cyclobutanes, while suffering from limitations of specific selectivity.
Jing-Si Wang, Kai Wu, Changzhen Yin, Kang Li, Yahao Huang, Jia Ruan, Ximin Feng, Peng Hu, Cheng-Yong Su   +8 more
doaj   +1 more source

Contemporary synthesis of bioactive cyclobutane natural products

Green Synthesis and Catalysis, 2023
Many cyclobutane natural products have intriguing biological properties that arise from their fascinating chemical structures. Cyclobutane natural products feature a cyclobutane scaffold as the core or as a part of the spirocyclic or fused cyclic core ...
Chunngai Hui, Zhuo Wang, Yusheng Xie, Junyang Liu   +3 more
doaj   +1 more source

Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives

Molecules, 2019
The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms.
Noha Hasaneen, Abdelaziz Ebead, Muhammad Murtaza Hassan, Hanan Afifi, Howard Hunter, Edward Lee-Ruff, Nadia S. El-Gohary, Azza R. Maarouf, Ali A. El-Emam   +8 more
doaj   +1 more source

9a-Phenyl-2,3,3a,3b,9a,9b-hexahydro-4H-furo[3‘,2’:3,4]cyclobuta- [1,2-b]chromen-4-one: A Flavone-Based [2 + 2]-Photocycloadduct

Molbank, 2021
The intermolecular [2 + 2]-photocycloaddition of the parent flavone molecule (4) as the triplet energy-accepting species and the electron-rich alkene 2, 3-dihydrofuran (5) was performed by visible-light-mediated triplet-sensitization with an iridium ...
Jens Lefarth, Jörg Neudörfl, Axel G. Griesbeck   +2 more
doaj   +1 more source

Stereoselective Synthesis of Bicyclo[3.1.1]Heptane Derivatives via Intramolecular Photocycloaddition Reaction

Natural Product Communications, 2012
Optically active 1,3-bridged cyclobutanes 10 of the bicyclo[3.1.1]heptane ring system and 1,2-bridged cyclobutanes 11 of the bicyclo[3.2.0]heptane ring system were produced by UV irradiation of α,β,γ,δ-unsaturated esters 9a and 9c-f.
Kiyoshi Honda, Mari Konishi, Manabu Kawai, Akihisa Yamada, Yasuhiko Takahashi, Yujiro Hoshino, Seiichi Inoue   +6 more
doaj   +1 more source

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, EarlyView.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources