Results 81 to 90 of about 14,856 (220)

Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

open access: yesActa Dermato-Venereologica, 2020
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
doaj   +1 more source

Synthesis of γ-cyclobutane amino acids via visible light [PDF]

open access: yes, 2019
In the present thesis an intramolecular visible light mediated [2+2] photocycloaddition of amide-linked dienes was developed to build up azabicycloheptanones which were transformed into γ-cyclobutane amino acids. Furthermore, these cyclobutane-containing
Kerres, Sabine Martha
core   +1 more source

Higher Overtone Vibrational Frequencies of Cyclobutane-D8 Using Lie Algebraic Framework

open access: yesEast European Journal of Physics
This research study employs a Lie algebraic framework to investigate the second and third overtone vibrational frequencies and their combination bands in cyclobutane-d8 (C4D8).
A. Ganapathi Rao   +2 more
doaj   +1 more source

Tetra-tert-butyl 13,14-dioxapentacyclo[8.2.1.14,7.02,9.03,8]tetradeca-5,11-diene-5,6,11,12-tetracarboxylate

open access: yesActa Crystallographica Section E, 2012
The stereochemistry of the title compound, C32H44O10, at the cyclobutane ring is cis-anti-cis. The molecule lies across an inversion center. In the crystal, weak C—H...O hydrogen bonds connect molecules into chains along [100], forming R22(6 ...
Alan J. Lough, Kelsey Jack, William Tam
doaj   +1 more source

Overview of Photochemical Reactions for the Synthesis of Aza and Oxa‐Spirocyclic Compounds Under Visible Light Irradiation

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj   +4 more
wiley   +1 more source

Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair

open access: yesNature Communications, 2017
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Hiroyuki Niida   +14 more
doaj   +1 more source

Cyclobutane-1,2-dione

open access: yesActa Crystallographica Section E Structure Reports Online, 2007
The title compound, C4H4O2, was prepared as an inter­mediate in the synthesis of α-hydroxy­cyclo­propane­carboxylic acid. The structure of this inter­mediate has only been deduced previously from 1H NMR spectra, elemental analysis or chemical derivatization.
Richard Betz, Peter Klüfers
openaire   +1 more source

N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions

open access: yesChemistry – A European Journal, Volume 32, Issue 33, 1 September 2026.
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero   +8 more
wiley   +1 more source

A Physical Organic Odyssey: From the Ultrafast Dynamics of Carbenes and Nitrenes to Contemporary Chemical Biology and Drug Discovery

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 9, September 2026.
Physical organic chemistry transforms photoaffinity labeling from empirical photochemistry into rational probe design. By measuring reactive‐intermediate lifetimes, pathways, and selectivity, Platz's legacy connects carbene and nitrene mechanisms to modern chemoproteomics, enabling more precise protein labeling and drug‐discovery maps.
Bin Yang, Jin Wang
wiley   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 5, Page 1138-1149, September/October 2026.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan   +3 more
wiley   +1 more source

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