Results 81 to 90 of about 14,856 (220)
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
doaj +1 more source
Synthesis of γ-cyclobutane amino acids via visible light [PDF]
In the present thesis an intramolecular visible light mediated [2+2] photocycloaddition of amide-linked dienes was developed to build up azabicycloheptanones which were transformed into γ-cyclobutane amino acids. Furthermore, these cyclobutane-containing
Kerres, Sabine Martha
core +1 more source
Higher Overtone Vibrational Frequencies of Cyclobutane-D8 Using Lie Algebraic Framework
This research study employs a Lie algebraic framework to investigate the second and third overtone vibrational frequencies and their combination bands in cyclobutane-d8 (C4D8).
A. Ganapathi Rao +2 more
doaj +1 more source
The stereochemistry of the title compound, C32H44O10, at the cyclobutane ring is cis-anti-cis. The molecule lies across an inversion center. In the crystal, weak C—H...O hydrogen bonds connect molecules into chains along [100], forming R22(6 ...
Alan J. Lough, Kelsey Jack, William Tam
doaj +1 more source
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj +4 more
wiley +1 more source
Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Hiroyuki Niida +14 more
doaj +1 more source
The title compound, C4H4O2, was prepared as an intermediate in the synthesis of α-hydroxycyclopropanecarboxylic acid. The structure of this intermediate has only been deduced previously from 1H NMR spectra, elemental analysis or chemical derivatization.
Richard Betz, Peter Klüfers
openaire +1 more source
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Physical organic chemistry transforms photoaffinity labeling from empirical photochemistry into rational probe design. By measuring reactive‐intermediate lifetimes, pathways, and selectivity, Platz's legacy connects carbene and nitrene mechanisms to modern chemoproteomics, enabling more precise protein labeling and drug‐discovery maps.
Bin Yang, Jin Wang
wiley +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source

