Results 61 to 70 of about 23,086 (229)
On the mechanism of the reaction of enamines and dimethyl acetylenedicarboxylate (DMAD) in polar and apolar solvents [PDF]
, 1982 [2+2]-Cycloadducts of enamines and DMAD, formed in apolar solvents, isomerize to pyrrolizine derivatives under mild conditions in protic polar solvents like methanol and 1 ...
Reinhoudt, D.N. +3 more
core +3 more sources
Cyclobutanes in Small‐Molecule Drug Candidates
ChemMedChem, 2022 AbstractCyclobutanes are increasingly used in medicinal chemistry in the search for relevant biological properties. Important characteristics of the cyclobutane ring include its unique puckered structure, longer C−C bond lengths, increased C−C π‐character and relative chemical inertness for a highly strained carbocycle.
Marnix R. van der Kolk +3 more
openaire +4 more sources
Spectroscopic analysis of bacterial photoreactivation
Photochemistry and Photobiology, Volume 101, Issue 2, Page 494-504, March/April 2025.This study investigates the effectiveness of fluorescence and Raman spectroscopy in detecting bacterial photoreactivation. Fluorescence spectroscopy shows limitations, because the intense fluorescence of tryptophan and tyrosine masks fluorescence emitted by thymine molecules.
Keyvan Khosh Abady +4 more
wiley +1 more source
Asymmetric Hydrogenation in Water by a Rhodium Complex of Sulfonated 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (binap) [PDF]
, 1993 The synthesis of sulfonated 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (binap) is reported; a rhodium complex of this ligand is the first to perform asymmetric hydrogenation in neat water with optical yields as high as those obtained in nonaqueous ...
Davis, Mark E., Wan, Kam-to
core +1 more source
Photochemistry and Photobiology, EarlyView.Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye +5 more
wiley +1 more source
ChemistryEuropeHerein, an efficient transference of axial chirality from enantiomerically enriched borylalkylidenecycloalkanes to point chirality is disclosed through the synthesis of spirocyclic valuable compounds via cyclopropanation, borylcyclopropanation ...
Nerea Iragorri +4 more
doaj +1 more source
Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]
, 2008 DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core +1 more source
Photochemistry and Photobiology, EarlyView.In a rabbit surgical field model seeded with polymicrobial flora, a single dose of 222‐nm UV‐C (500 mJ/cm2) markedly reduced bacterial colonies, achieving a bactericidal effect comparable to 254‐nm UV‐C (200 mJ/cm2), while no UV‐C irradiation showed heavy growth. Wound healing did not differ among groups. Microbiota profiling detected SSI‐relevant taxa
Tomoaki Fukui +11 more
wiley +1 more source
r-1,t-3-Bis[4-(dimethylamino)phenyl]-c-2,t-4-bis(pyridin-4-yl)cyclobutane
Acta Crystallographica Section E, 2014 The title compound, C30H32N4, was synthesized by the photodimerization of trans-4-{2-[4-(dimethylamino)phenyl]ethenyl}pyridine in benzene upon irradiation with UV light.
Shuguang Zhang, Junpeng Zhuang
doaj +1 more source
Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine
Photochemistry and Photobiology, EarlyView.6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes +6 more
wiley +1 more source