Results 61 to 70 of about 14,856 (220)

Ionizing Radiation and Ultraviolet Light Irradiation‐Associated DNA Damage Increasing Genomic Instability Risk

open access: yesCancer Science, EarlyView.
UV irradiation induces two major types of pyrimidine dimers, CPDs and 6–4PPs. Whereas 6–4PPs efficiently induce cell‐cycle arrest, CPDs do not and frequently persist into S phase. As a result, DSBs can arise in the presence of unrepaired CPDs after 6–4PPs have been repaired, increasing the risk of genomic instability.
Ken‐ichi Yoshioka   +2 more
wiley   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson   +6 more
wiley   +1 more source

Thermal Cyclobutane Ring Formation

open access: yes
The cyclobutane moiety is found in many natural products and bioactive compounds. A high number of total syntheses of cyclobutane-containing natural products has been reported. In addition, cyclobutanes and cyclobutenes are useful synthetic intermediates
Almendros, Pedro, Aragoncillo, Cipriano
core   +1 more source

[3-Benzoyl-2,4-bis(3-nitrophenyl)cyclobutyl](phenyl)methanone

open access: yesActa Crystallographica Section E, 2012
The asymmetric unit of the title compound, C30H22N2O6, comprises a half-molecule of the cyclobutane derivative. The least-squares planes defined by the respective C atoms of the aromatic substituents intersect at angles of 76.81 (7) and 89.22 ...
Prakash S. Nayak   +5 more
doaj   +1 more source

Antibacterial Activity of Synthesized Derivatives of Purpurin Containing Cyсlopropane and Cyclobutane Fragment

open access: yesEurasian Chemico-Technological Journal, 2020
The present study is a continuation of the scientific research works for the synthesis of anthraquinonе-containing derivatives with cyclic ring systems by the interaction of 1,2,4-trihydroxyanthraquinone (purpurin) with cyclopropanecarboxylic acid ...
Т. V. Kharlamova   +3 more
doaj   +1 more source

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara   +3 more
wiley   +1 more source

[2+2]-Photocycloadditions of 2-Acetoxy-1,4-naphthoquinone and Structure Determination of the Main Photoadducts

open access: yesPhotochem
The [2+2]-photocycloaddition of 2-acetoxy-1,4-naphthoquinone with 1,1-diphenylethylene, styrene and cyclopentene was conducted in a conventional batch reactor.
Madyan A. Yaseen   +3 more
doaj   +1 more source

Spectroscopic analysis of bacterial photoreactivation

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 494-504, March/April 2025.
This study investigates the effectiveness of fluorescence and Raman spectroscopy in detecting bacterial photoreactivation. Fluorescence spectroscopy shows limitations, because the intense fluorescence of tryptophan and tyrosine masks fluorescence emitted by thymine molecules.
Keyvan Khosh Abady   +4 more
wiley   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

open access: yesPhotochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto   +8 more
wiley   +1 more source

UV-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells

open access: yes, 1986
We used a simian virus 40-based shuttle vector plasmid, pZ189, to determine the role of pyrimidine cyclobutane dimers in UV light-induced mutagenesis in monkey cells. The vector DNA was UV irradiated and then introduced into monkey cells by transfection.
Munson, P. J.   +5 more
core   +2 more sources

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