Results 61 to 70 of about 400 (141)
The stereochemistry of the title compound, C32H44O10, at the cyclobutane ring is cis-anti-cis. The molecule lies across an inversion center. In the crystal, weak C—H...O hydrogen bonds connect molecules into chains along [100], forming R22(6 ...
Alan J. Lough, Kelsey Jack, William Tam
doaj +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Hiroyuki Niida +14 more
doaj +1 more source
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
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ABSTRACT The overuse of synthetic pesticides in agriculture has raised significant environmental and health concerns. Biopesticides have emerged as viable, environmentally compatible alternatives. However, recent comprehensive reviews integrating all biopesticide categories and emphasizing their contribution to synthetic‐pesticide‐free and health‐safe ...
Molalign Assefa +5 more
wiley +1 more source
Self‐nanostructuring of redox‐active organic small molecules through in situ electrochemical postcrosslinking enabled an aqueous‐processed, stable, fast‐rechargeable organic electrode even with a high active content ratio and mass loading. ABSTRACT Redox‐active organic materials (ROMs) for batteries are emerging as sustainable alternatives to inorganic
Kyunam Lee +16 more
wiley +1 more source
This research introduces an ortho‐palladated oxazolone moiety that can undergo rapid and reversible photocycloaddition by low‐intensity green light irradiation. Integration of such a photoresponsive function into crosslinked polymer structures enables rapid photo‐ and thermo‐switching of polymer properties, presenting a unique light‐directed covalent ...
Wai Lean Koay +7 more
wiley +1 more source
Four-membered carbocycles are among the most sought-after backbones which are commonly found in biologically active molecules. However, difficulties on their producing are existing due to its highly strained ring system.
Xing-Wei Gu, Yan-Hua Zhao, Xiao-Feng Wu
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Synthesis of Cis-Diammine (1,1-cyclobutane dicarboxylate) Platinum(II) [PDF]
Platinum-based anticancer drugs are chemotherapeutic agents to treat cancer. Carboplatin (cis diammine cyclobutane dicarboxylate platinum (II)) is a second generation drug that has less toxic than cisplatin, allowing for high dosages. In the first stage,
Ali Nemati kharat +3 more
doaj
Bridging the gap. Beyond deck functionalization, the ethylene bridges of [2.2]paracyclophanes offer a largely unexploited reactivity landscape. This review showcases strategies to functionalize these bridges and leverage them to build novel cyclophane architectures.
Rongyu Sun +3 more
wiley +1 more source

