Results 121 to 130 of about 22,823 (226)
Roles of Alp and Prt Regulons in the Response of Pseudomonas aeruginosa to UV‐C Light
Our results show that LexA‐regulated genes are the first to be induced after DNA damage, while autolysis functions controlled by the Alp system are the last. Death by UV is mediated primarily by Alp or Prt systems, depending on the Pseudomonas aeruginosa subline. ABSTRACT UV light is a well‐studied environmental DNA damaging agent.
Marina R. B. Fonseca +6 more
wiley +1 more source
A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin +7 more
wiley +1 more source
Mechanochemistry of cyclobutanes
AbstractThe field of polymer mechanochemistry has been revolutionized by implementing force-responsive functional groups—mechanophores. The rational design of mechanophores enables the controlled use of force to achieve constructive molecular reactivity and material responses.
Roberto Obregon, Junpeng Wang
openaire +1 more source
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila +6 more
wiley +1 more source
Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen
Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Mixed quartic-harmonic oscillators: A study of the ring puckering vibration of a cyclic amino acid dimer [PDF]
Andrews, D. L. +3 more
core +1 more source
Ring expansion of cyclobutylmethylcarbenium ions to cyclopentane or cyclopentene derivatives and metal-promoted analogous rearrangements [PDF]
D'hooghe, Matthias +2 more
core +1 more source
Mapping the Undirected Borylation of C(sp3)-H Bonds in Strained Rings. [PDF]
La C +3 more
europepmc +1 more source

