Results 301 to 310 of about 172,270 (336)
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Chemical Communications, 2022
Cyclodextrins effectively work as mechanical-force transducers.
Yuki Sugita +3 more
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Cyclodextrins effectively work as mechanical-force transducers.
Yuki Sugita +3 more
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International Journal of Pharmaceutics, 2013
Although cyclodextrins (CDs) have been studied for over 100 years and can be found in at least 35 pharmaceutical products, they are still regarded as novel pharmaceutical excipients. CDs are oligosaccharides that possess biological properties that are similar to their linear counterparts, but some of their physicochemical properties differ.
Sergey V, Kurkov, Thorsteinn, Loftsson
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Although cyclodextrins (CDs) have been studied for over 100 years and can be found in at least 35 pharmaceutical products, they are still regarded as novel pharmaceutical excipients. CDs are oligosaccharides that possess biological properties that are similar to their linear counterparts, but some of their physicochemical properties differ.
Sergey V, Kurkov, Thorsteinn, Loftsson
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Toxicologic Pathology, 2008
β-cyclodextrin (β-CD) and other cyclodextrins (CDs) have utility for solubilizing and stabilizing drugs; however, some are nephrotoxic when administered parenterally. A number of workers have attempted to identify, prepare, and evaluate various CD derivatives with superior inclusion complexation and maximal in vivo safety for various biomedical uses ...
Valentino J, Stella, Quanren, He
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β-cyclodextrin (β-CD) and other cyclodextrins (CDs) have utility for solubilizing and stabilizing drugs; however, some are nephrotoxic when administered parenterally. A number of workers have attempted to identify, prepare, and evaluate various CD derivatives with superior inclusion complexation and maximal in vivo safety for various biomedical uses ...
Valentino J, Stella, Quanren, He
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ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Eric, Engeldinger +2 more
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Eric, Engeldinger +2 more
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International Journal of Pharmaceutics, 2017
γ-Cyclodextrin (γCD) is a cyclic oligosaccharide formed by bacterial digestion of starch and used as solubilizing agent and stabilizer in a variety of pharmaceutical and food products. γCD is a large (molecular weight 1297Da) hydrophilic molecule that does not readily permeate biological membranes and is rapidly digested by bacteria in the ...
Phennapha, Saokham, Thorsteinn, Loftsson
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γ-Cyclodextrin (γCD) is a cyclic oligosaccharide formed by bacterial digestion of starch and used as solubilizing agent and stabilizer in a variety of pharmaceutical and food products. γCD is a large (molecular weight 1297Da) hydrophilic molecule that does not readily permeate biological membranes and is rapidly digested by bacteria in the ...
Phennapha, Saokham, Thorsteinn, Loftsson
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Self-Association of Cyclodextrins and Cyclodextrin Complexes
Journal of Pharmaceutical Sciences, 2004Cyclodextrins are useful functional excipients, which are being used in an ever-increasing way to camouflage undesirable pharmaceutical characteristics, especially poor aqueous solubility. It has generally been assumed that the mechanism whereby cyclodextrins exert their effects, especially their augmentation of solubility, is via the formation of ...
Thorsteinn, Loftsson +2 more
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Functional cyclodextrins. 1. Chloroacetylated cyclodextrins
Die Angewandte Makromolekulare Chemie, 1998The paper discusses the synthesis of the chloroacetylated derivatives of α-, β- and γ-cyclodextrins. These novel functionalized products can be used both in the synthesis of some conjugates with bioactive substances by covalent bonding and/or for inclusion of hydrophobic compounds.
Adrian Carpov +2 more
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Journal of inclusion phenomena and macrocyclic chemistry, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
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AbstractFor Abstract see ChemInform Abstract in Full Text.
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Cyclodextrins and Antioxidants
Critical Reviews in Food Science and Nutrition, 2013In recent years, the growth of the functional foods industry has increased research into new compounds with high added value for use in the fortification of traditional products. One of the most promising functional food groups is those enriched in antioxidant compounds of a lipophilic nature.
José Manuel, López-Nicolás +2 more
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