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Cycloferon in local immunotherapy in patients with virus-associated rhinitis

Vestnik otorinolaringologii, 2021
Evaluation of the effectiveness of various schemes of local immunotherapy in immunocompromised patients with allergic rhinitis was carried out.A comparative analysis of the treatment of 72 patients with allergic rhinitis, divided into groups: I (main, n=21), which included immunocompromised patients who received sublingual allergen-specific ...
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[Efficacy of cycloferon in the treatment of brucellosis].

Klinicheskaia meditsina, 2010
Therapeutic potential of cyclopheron was evaluated as exemplified by the treatment of patients with chronic brucellosis. Positive clinical dynamics during combined treatment including cyclopheron is apparent as reduced duration of intoxication and inflammation, improved quality of life, decreased frequency of exacerbation of the infectious process and ...
E P, Liapina   +4 more
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[Intracellular localization of cycloferon, its binding with DNA and stimulation of cytokines expression after exposure to cycloferon].

Tsitologiia, 2000
Despite the wide usage of immunomodulating preparates including interferon inducers in medical practice little is known about their mechanism of action. We investigated some theoretical aspects of action of potent interferon inducer--cycloferon (10-carboxymethyl-9-acridanone), such as intracellular localization, ability to DNA binding and cytokine ...
A L, Kovalenko   +4 more
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[The use of cycloferon in experimental radiotherapy of tumors].

Voprosy onkologii, 1999
The biological activity of cycloferon (CF) used in interferon manufacture has been investigated for its therapeutic and prophylactic properties which may be used for radiotherapy of glioma. It was demonstrated in experiments on rats that use of CF is most effective at an early stage of irradiation due to decrease in tumor mass which does not occur in ...
S D, Ivanov   +6 more
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[Cycloferon therapy of cytomegalovirus infection in monkeys].

Eksperimental'naia i klinicheskaia farmakologiia, 2013
Cytomegalovirus (CMV) infection is a wide-spread disease throw humans and monkeys, which and associated with various diseases. The development of this infection in human organism is much like that in rhesus macaque, which makes CMV-infected monkeys adequate model for studying and elaborating prophylactic and therapeutic measures against this disease in
M V, Mezentseva   +3 more
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[Cycloferon in treating duodenal ulcers in rats].

Eksperimental'naia i klinicheskaia farmakologiia, 2002
The possibility of using cycloferon (interferon inductor) for a complex treatment (in combination with the main drug solcoseryl possessing pronounced therapeutic properties) of duodenum ulcers was experimentally studied in male rats. The experiments showed a considerable difference in the interferon status of animals with model duodenum ulcers treated ...
V V, Bul'on   +7 more
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[Effectiveness of immunomodulating therapy of pulmonary tuberculosis with cycloferon].

Klinicheskaia meditsina, 2014
Cycloferon was used to treat newly diagnosed, recurrent and long-standing pulmonary TB. The dose of 7,5 g combined with antibacterial therapy caused no complications. The effectiveness of this therapy based on the generally-accepted criteria was significantly higher than standard treatment but varied depending on the character of pathological process ...
V M, Kolomiets, N V, Rubleva
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