Clinical efficacy of the immunomodulatory agent cycloferon (tablets) in viral respiratory infections: Results of a systematic review and meta-analysis [PDF]
The authors carried out a systematic review and subsequent meta-analysis of randomized clinical trials evaluating the efficacy of the immunomodulator agent cycloferon as tablets in adults and children with viral respiratory diseases.
N K Mazina +5 more
doaj +2 more sources
Transcriptional activity of TLR/RLR receptor genes in macrophage-like cells under the influence of drugs based on acridoneacetic acid [PDF]
Activation of Toll-like receptors (TLRs) is one of the earliest indicators of functional activation of the innate immune system. Therefore, the development of drugs that stimulate the transcription of TLR/RLR genes and at the same time are “multi-target”
A. N. Narovlyansky +8 more
doaj +2 more sources
New approaches to therapy of oral inflammatory diseases [PDF]
The purpose of the work is to prescribe combined treatment in order to determine the efficiency of cycloferon liniment. Materials and methods. 80 patients suffering from such inflammatory disease of parodentium as herpetic stomatitis and periodontitis ...
Soboleva L.A. +3 more
doaj +1 more source
INFLUENCE OF CYCLOFERON ON THE CELLULAR SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO IN PATIENTS WITH INFECTIOUS MONONUCLEOSIS CAUSED BY EPSTEIN– BARR VIRUS [PDF]
Our aim was to study the effect of cycloferon on in vitro susceptibility of peripheral blood leukocytes to interferon-α2 in children with infectious mononucleosis in acute phase caused by Epstein-Barr virus (EBV).
L. M. Kurtasova +3 more
doaj +2 more sources
This work is devoted to the actual problem of studying modern ideas about the systemic treatment of brain tumors, in particular on the implementation and effectiveness of modern methods of immunomodulation in neuro-oncology.
M. Mukhacheva, B. Beyn
doaj +2 more sources
Infectious mononucleosis in children: clinical and laboratory rationale and economic efficiency of application of immunocorrectors [PDF]
Objective: to select the optimal, clinically and economacally effective immunocorrector for the treatment of immune-EBV — mononucleosis in children. Materials: 400 patients with primary Epstein — Barr virus infection aged 1 to 14 years. Results.
Shvedova N.M. +3 more
doaj +1 more source
Improvement of therapy of inflammatory dieseases of parodentium in patients with focal tuberculosis [PDF]
The purpose of the study is to determine clinical and pathogenetic efficacy of cycloferon liniment in the combined therapy of periodontitis of patients with focal tuberculosis.
Shuldyakov А.А. +3 more
doaj +2 more sources
ACTIVATION OF GENES CONTROLLING THE IMMUNE SIGNALING PATHWAYS: DIFFERENTIAL INDIVIDUAL SENSITIVITY OF HUMAN BLOOD CELLS FOR INTERFERON PREPARATIONS AND IFN INDUCERS [PDF]
We have studied dose effects of several Interferon (IFN) inducers, i.e., Genfaxon (beta-1 IFN), Cycloferon and Immunomax upon expression of six genes controlling the signaling in immune pathways (TLR3, TLR4, RIG1, IRF3, IPS, B2M), by means of real-time ...
T. M. Sokolova +4 more
doaj +2 more sources
Purpose. To study the clinical effectiveness of the system of complex treatment of optic neuritis (ON) associated with herpesvirus infection(HVI), including methods of immunopharmacotherapy. Patients and methods. The clinical study involved 55 people (55
D. A. Povaliaeva +3 more
doaj +2 more sources
Clinical and pathogenetic approaches to development of parodontitis therapy in patients with chronic hepatitis С [PDF]
The research goal in to determine clinical and pathogenetic efficacy of Cycloferon liniment in the combined therapy of parodontitis in patients with chronic hepatitis C. Examination and treatment of 50 patients were conducted.
E.N. Blinnikova +4 more
doaj +1 more source

