Results 101 to 110 of about 122,535 (318)
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He +8 more
wiley +1 more source
Atroposelective Suzuki–Miyaura Coupling to Form 2‐Amino‐2′‐Hydroxybiphenyls Enabled by sRuPhos
We report a new chiral phosphine ligand, sRuPhos, which permits the highly enantioselective Suzuki–Miyaura coupling of ortho‐aniline and ortho‐phenol building blocks. This results in 2‐amino‐2′‐hydroxybiphenyls with very high enantiomeric excesses, products that will have application in pharmaceutical synthesis and ligand design for catalysis ...
Hamzah Sharif +3 more
wiley +2 more sources
Mass spectrometry in structural and stereochemical problems. Part 178 - The electron-impact promoted fragmentation of 1,2-cyclohexene oxide [PDF]
Mass spectra of 1,2-cyclohexane oxide and three deuterium labeled ...
Brown, P., Djerassi, C., Strong, M. K.
core +1 more source
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang +19 more
wiley +1 more source
Photothermal Conversion Promotes Challenging SNAr for Facile C─N Bond Formation
Photothermal conversion enables facile aromatic C─N bond formation via red light irradiation. A variety of inter‐ and intramolecular SNAr transformations are achieved under mild, schematically simple conditions. Additionally, a thermally promoted halogen exchange mechanism provides access to aryl bromides, chlorides, and fluorides – making this ...
Megan E. Matter +2 more
wiley +2 more sources
Probing structural relaxation in complex fluids by critical fluctuations
Complex fluids, such as polymer solutions and blends, colloids and gels, are of growing interest in fundamental and applied soft-condensed-matter science.
A. F. Kostko +32 more
core +1 more source
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han +6 more
wiley +1 more source
Stereodivergent Synthesis of Three Contiguous Stereogenic Centers by Cu/Ir‐Catalyzed Borylallylation
An alkene borylallylation strategy enabled by cooperative Cu/Ir‐catalysis has been uncovered for accessing three contiguous stereogenic centres. This strategy is notable given the inherent challenges of constructing molecules with multiple stereocenters while maintaining high selectivity bearing diverse functional groups.
Suman Das +2 more
wiley +2 more sources
Kaolin one of clay minerals has been employed as a SiO2 source and produced a mixture of two type SiO2, quartz and quartz alpha, with the amount of 60 % of kaolin used. The SiO2 produced had been diverted to silica gel and used as supporting agent for Ni/
Tresye Utari +2 more
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