Results 121 to 130 of about 41,336 (320)
Archiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023 Based on a simplified version of the morphinan scaffold, 3‐[3‐(phenalkylamino)cyclohexyl]phenol analogues were designed, synthesized and evaluated for their µ‐opioid receptor (MOR) antagonist activity in vitro and in silico. Docking studies indicate a peculiar combination of C‐1 stereochemistry and N‐substitutions as feasibly essential for MOR‐ligand ...
Graziella Tocco +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.By retrosynthetically analyzing the molecular structure of an intercalator, clear design principles toward supramolecular sequestration can be obtained. Investigating a model supramolecular polymer in the presence of these additives offers a general approach toward dilution‐induced polymerization and complex hybrid systems of dual sequestration and ...
Nils Bäumer +2 more
wiley +2 more sources
Spiro-compounds. Part I. A New Route to Spiro compounds. Synthesis of cycloHexane-spiro- cyclopentane [PDF]
, 1936 NRIPENDRA NATH CHATTERJEE
openalex +1 more source
Beilstein Journal of Organic Chemistry, 2016 2,2-Dimethyl-5-phenyl-1,1,3,3-tetrafluororocyclohexane has been prepared and characterised as an example of a facially polarised cyclohexane containing 1,3 related CF2 groups. The dipolar nature of the ring arises from the axial orientation of two of the
Mathew J. Jones +4 more
doaj +1 more source
Angewandte Chemie, EarlyView.The first application of pure hydrocarbon materials as hosts in phosphorescence‐sensitized multi‐resonance thermally activated delayed fluorescence (MR‐TADF) OLEDs is reported. Blue MR‐TADF OLEDs using either DtBuCzB or v‐DABNA as emitter and either FIrpic, fac‐Ir(tpz)3 or CN−Ir as sensitizer, achieved very high maximum external quantum efficiencies ...
Yue‐Jian Yang +10 more
wiley +2 more sources
Nanoscale heterogeneous phase separation kinetics in binary mixtures: Multistage dynamics [PDF]
arXiv, 2016 In order to find a measure of the dynamical features of phase separation kinetics during spinodal decomposition of a liquid binary mixture (like water and cyclohexane , water and 2,6 lutidiene or methanol and cyclohexane), we study both the initial fast exponential-like growth (the Cahn-Hilliard regime) and the subsequent cross-over to a much slower ...
arxiv
Supramolecular Gels as Active Tools for Reaction Engineering
Angewandte Chemie, EarlyView.The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley +2 more sources
Enantioconvergent Deacylative Functionalization toward α‐Quaternary Nitriles
Angewandte Chemie, EarlyView.An enantioconvergent quaternary‐to‐quaternary synthesis of α‐chiral nitriles has been enabled. By replacing the acyl group with a variety of allyl, propargyl, and benzyl motifs, the functional group swap can convert easily available β‐ketonitriles to assorted quaternary stereocenters en route to bioactive molecules of broad interests.
Minghao Zhang, Zhongxing Huang
wiley +2 more sources
Solvent Quality and Nonbiological Oligomer Folding: Revisiting Conventional Paradigms [PDF]
arXivWe report on extensive molecular dynamics atomistic simulations of a \textit{meta}-substituted \textit{poly}-phenylacetylene (pPA) foldamer dispersed in three solvents, water \ce{H2O}, cyclohexane \ce{cC6H12}, and \textit{n}-hexane \ce{nC6H14}, and for three oligomer lengths \textit{12mer}, \textit{16mer} and \textit{20mer}.
arxiv
Size‐Programmable Matteson‐Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones
Angewandte Chemie, EarlyView.An iterative boron‐homologation approach is developed to enable programmable syntheses of various carbocycles with different sizes stereoselectively from simple precursors. This method utilizes an electron‐withdrawing group (EWG) as a handle to enable intramolecular Matteson‐type couplings, leading to diastereoselective and enantioselective ring ...
Woohyun Jo +4 more
wiley +2 more sources