Results 221 to 230 of about 119,767 (324)

Bioactivity Profiles of Progressively Ring‐Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto‐Piperazines as Antitrypanosome Agents

open access: yesChemBioChem, EarlyView.
All‐cis‐fluorinated cyclohexyl motifs with progressively increasing levels of fluorine are introduced into the WKYMVm peptide and a class of keto‐piperazine derivatives and assayed against the FPR2 receptor or the parasite Trypanosoma brucei, respectively.
Mengfan He   +6 more
wiley   +1 more source

Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies

open access: yesChemBioChem, EarlyView.
The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García   +2 more
wiley   +1 more source

Synthesis of an N‐Galactosyl Norbornane Aziridine and its Potent Mixed Inhibition of Aspergillus oryzae β‐Galactosidase

open access: yesChemBioChem, EarlyView.
An N‐galactosyl aziridine is found to have μM range mixed inhibition constants (Ki and Ki’) for a fungal β‐galactosidase. Aziridine‐bearing cyclic polyols are established as irreversible covalent inhibitors of glycosyl hydrolases and have been employed as activity‐based probes. In the present study, the stereoselective synthesis of a novel N‐galactosyl
Aaron McCormack   +3 more
wiley   +1 more source

Fe─Co Synergism in the Heterogeneous Catalytic Conversion of Cyclohexane to KA Oil

open access: yesChemCatChem, EarlyView.
This research aimed to investigate the potential of heterogeneous Fe‐Co catalysts supported on Alumina in the oxidation of cyclohexane to cyclohexanol and cyclohexanone (KA oil). Different catalysts have been synthesized by sol‐immobilization, wetness impregnation and inverse microemulsion, revealing a different catalytic activity and selectivity ...
Marta Stucchi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy