Results 221 to 230 of about 109,025 (272)

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel   +2 more
wiley   +1 more source

Modifications of NU-9, a potent protein aggregation inhibitor. Properties and activity in a cellular model of amyotrophic lateral sclerosis. [PDF]

open access: yesBioorg Chem
Elmansy MF   +8 more
europepmc   +1 more source

Laurdan: Clarifying Photophysics and Advancing the Characterization of Extracellular Vesicles

open access: yesChemPhysChem, Volume 27, Issue 5, 13 March 2026.
Biophysical properties of extracellular vesicles (EVs) reflect their composition and membrane organization. We introduce a novel approach using time‐resolved emission spectra (TRES) phasor analysis of the polarity‐sensitive probe Laurdan to characterize membranes with complex compositions.
Petra Riegerová   +8 more
wiley   +1 more source

Rational design and applications of piperazine and cyclohexane ionizable lipids for PKU and SSADH deficiency. [PDF]

open access: yesMol Ther Nucleic Acids
Son J   +23 more
europepmc   +1 more source

Chemical Profiling of Latvian Propolis: Regional Variations and Botanical Origins. [PDF]

open access: yesMolecules
Papakosta F   +7 more
europepmc   +1 more source

Visible-light induced click reactions of acylsilanes with pyruvate electrophiles. [PDF]

open access: yesChem Sci
Pilkington RL   +4 more
europepmc   +1 more source

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